Proteins and Protein Structure

Chemical

________ and physical interactions cause protein folding.

Chaperones

________: protein molecules that assist the proper folding of other proteins.

Shape

________ is specific and important to function.

protein chains

The ________ are held together by intermolecular hydrogen bonding.

Protein

________ can be formed from several copies of the same polypeptide.

Amino acids

________: the building blocks of proteins.

Amino acids

the building blocks of proteins

Or may be multimeric

composed from different polypeptides

Chaperones

protein molecules that assist the proper folding of other proteins

Proteins are composed of

carbon, hydrogen, oxygen, nitrogen, and small amounts of other elements, notably sulfur

Secondary structure

α helices and β pleated sheets

Tertiary structure

Folding gives protein a complex 3D shape
This is the final level of structure for a single polypeptide chain

Quaternary structure

Made up of two or more polypeptides

Chaperone Functions

Folding and refolding

Preservation of the unfolded state

Facilitation to transport

Block to aggregation

Disaggregation

Degradation

Assembly/disassembly of oligomeric complexes

Facilitation of signaling processes