The nucleus part 2

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Last updated 10:36 AM on 10/6/26
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27 Terms

1
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DNA structure compared to RNA

No -OH group on carbon 2

very stable

role: long term use

2
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RNA structure compared to DNA

-OH group on carbon 2

not stable (very reactive)

role: short erm use

3
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explain how nucleotides are joined together

a phosphodiester bond forms via a condensation reaction between the 5’ carbon of the sugar from one nucleotide to the 3’ carbon on the sugar of the next carbon

releasing one molecule of water

4
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which direction do we read the DNA base sequence?

start from the 5’ to the 3’ end

5
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why is the double helix shape of DNA useful?

it makes the DNA compact and very stable

6
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how many hydrogen bonds between A and T?

2

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how many hydrogen bonds between G-C?

3

8
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describe the position of the DNA bases to the helix

The Base pairs are perpendicular to the axis of the helix.

9
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One turn has how many base pairs?

10.4 base pairs

10
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<p>Label the major and minor grooves</p>

Label the major and minor grooves


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11
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What is the term for DNA wrapped around proteins in eukaryotic cells?

Chromatin

12
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how many chromosomes do humans have?

23 pairs

therefore 46 chromosomes in total

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how many chromosomes do gametes have?

23 in chromosomes in total

14
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how many homologous and non homologous pairs of chromosomes do humans have?

22 homologous pairs

1 non-homologous pair (XY or XX sex chromosome)

15
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how many nucleotide pairs of DNA does the human genome contain?

3.1 x 10^9 nucleotide pairs

16
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compare Euchromatin and Heterochromatin

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17
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<p>Label this diagram of the nucleus</p>

Label this diagram of the nucleus

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18
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<p>label this diagram of the chromosome</p>

label this diagram of the chromosome

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19
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what is a nucleosome amde of?

  • 8 histone proteins (called a histone octamer) That is 2 each of: H2A, H2B, H3, and H4

  • 147 base pairs of DNA wrapped around it

  • It wraps 1.7 turns around this protein core


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what are nucleosomes separated by?

linker DNA

21
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what are the 4 core histones?

H2A, H2B, H3 & H4

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which 2 histones form dimers?

H2A and H2B

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what is the function of dimers?

they interact with the DNA within the nucleosome, stabilising its structure

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which 2 histones form tetramers?

H3 and H4

25
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what is the function of tetramers?

are involved in DNA wrapping and interactions with other nucleosomes

26
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what are the 2 linker histones?

H1 and H5

27
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As DNA is being compacted to form a chromosome state 5 the different structures it forms in order. include measurements.



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