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Section 4: Chemiosmosis + ATP Synthase lecture 16
Section 4: Chemiosmosis + ATP Synthase lecture 16
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What is chemiosmosis?
Using an H+ gradient to drive ATP synthesis.
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What is the proton motive force?
Stored energy in the electrochemical H+ gradient.
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Where is H+ concentration high in mitochondria?
Intermembrane space.
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Where is H+ concentration low in mitochondria?
Matrix.
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Which direction do H+ flow during chemiosmosis?
Intermembrane space → matrix.
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What protein allows H+ to flow back into the matrix?
ATP synthase.
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What does ATP synthase make?
ATP from ADP + Pi.
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What powers ATP synthase?
Flow of H+ down its electrochemical gradient.
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What does reversible ATP synthase mean?
It can either make ATP or use ATP to pump H+.
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How can ATP synthase run in reverse?
It hydrolyzes ATP to pump H+ against its gradient.
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What is the easiest chemiosmosis memory trick?
H+ falls downhill through ATP synthase and makes ATP.