immature cells in acute myelogenous leukemia

Metamyelocyte or Band?

Meta

Myeloblast

seen in AML- auer rods, fine chromatin, prominent nucleoli

M1 myeloblast without maturation

M2

bundle of auer rods, hypergranulation

M3 : promyelocytic

Monoblasts and promonocytes and neutrophil precursors seen

M4 : myelomonocytic

M5: Monoblasts

Striking poik, high number of RBC precursors

M6: Erythroblasts

Lymphoblasts with vacuoles

Micromegakaryocyte with blebbing

inclusion

toxic granulation

inclusion

Dohle bodies

inclusion seen in AML and MDS

psuedo pelger huet

nRBC

megakaryocyte

promyelocyte

myelocyte

metamyelocyte

plasma cell

smear of AML

myeloblasts with auer rods

smudge cells

M0

blast with no maturation (close to stem cell)

M1

myeloid blast without morphological maturation w/ auer rod

M1

more blasts w/ auer rods

M1

blasts with auer rods

M1

blasts and a psuedo pelger huet (on the right)

M1

blasts

M1

psuedo pelger huet and blast

M1

2 blasts and 2 psuedo pelger huet (chromatin indicates maturity)

M1

3 blasts and psuedo pelger huet

M2

blast with maturity (circled),

M3

promyelocytes - hypergranular

M3

promyelocyte - hypergranulation (assoc. with DIC bc the granules are thromboplastic substances so they are more likely to initiate clotting)

M3

promyelocyte w/ bundle of auer rods

M3

promyelocyte with fine granules

M4

myelomonocytic - monoblast

M4

monoblast - blue gray cytoplasm

myeloblast vs monoblast

M4

monoblast

M5

monoblast - tissue paper looking

M5

monoblast

M6 - erythroleukemia

rubriblast or nRBC

M6

erythroblasts / nrbc (dark cytoplasm)

M6

bi nucleated erythroblast/nrbc

M7 - megakaryocytic

megakaryocyte w/ blebbing

M7

micro megakaryocytes

M7

micro megakaryocyte with giant platelet

blast

blast

blast

blast

blast

blast

lymphocyte

lymphocyte

lymphocyte

lymphocyte

lymphocyte

lymphocyte

lymphocyte

lymphocyte

lymphocyte

myelocyte

myelocyte

myelocyte

myelocyte

metamyelocyte

metamyelocyte

metamyelocyte

metamyelocyte

metamyelocyte

metamyelocyte

metamyelocyte

band

band

band

band

thrombocythemia - too many plts

monocyte

monocyte

monocyte

monocyte

monocyte

monocyte

monocyte

monocyte

nrbc

band

CML - mature segs, immature granulocytes, **basophil (common), myelocytes

CML- myelocyte*

CML- myelocyte, band, seg, promyelocyte(nucleoli, granules)

CML- with rare blast

CML- basophils* present

CML- with eosinophilic characteristics

CML- myelocytes and metamyelocyte (center, kidney bean shape)

micromegakaryocyte and giant platelet - seen in leukemias

teardrops are associated with what condition?

myelofibrosis - theyre doing extramedullary hematopoesis

associated with

mononucleosis - reactive lymphs

eosinophil- allergies