MICR 300 Viruses Exam 3

realm

viria

kingdom

virae

phylum

viricota

class

viricetes

order

virales

family

viridae

subfamily

virinae

genus

virus

rigid protein coat surrounding a virus

capsid

protein subunits that make up capsids

capsomeres

the capsid together with the nucleic acid

nucleocapsid

viral proteins that link the envelope with nucelocapsid

matrix tegument proteins

Viral proteins embedded in the envelope

glycoprotein

capsid type

helical

capsid type

icosohedral

how many triangular faces do icosahedral capsids have?

20

membrane-bound viral attachment proteins that form spikes on viruses and facilitate attachment and entry to host cells

glycoproteins

infection of the gastrointestinal (GI) tract, leads to diarrhea, vomiting, and/or loss of appetite

gastroenteritis

pathogens that cause infection in developing fetuses or newbonds. This can occur in utero, during delivery, or after birth

TORCH

TORCH - T

toxoplasma gondii

TORCH - O

treponema pallidum, parvovirus B19, HIV, VZV

TORCH - R

rubella

TORCH - C

cytomegalovirus

TORCH - H

herpes simplex virus

viral replication: recognition of target cell → attachment → entry → uncoating

early phase

viral replication: genome replication → transcription and translation → assembly → release

late phase

viral replication: phase when viral nucleic acid is uncoated from the capsid and no infectious virus can be detected inside the host cell; time between host infection and start of virus production

eclipse period

viral replication: no extracellular virus detectable (includes eclipse period); ends with release of new viruses

latent period

yield of infectious virus per cell, including time required for a single viral replication cycle

burst size

defective particles that result from mutations and errors during viral replication

noninfectious particles

the cell types that are susceptible and permissive to binding by viral attachment proteins

tropism

the specific species that have the cell types with receptors that a virus can bind to

host range