At least one of the R's on nitrogen must be H+ in order for it to be acidic. pKa:5-10 (acidic)
5
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Thiol
pka: 8- 10.5 (acidic)
6
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Phenol
pKa: 9-10 (acidic)
7
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Aliphatic or alicyclic
are NEUTRAL
8
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Guanadine
Strongest base. pKa: 12-13
9
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Amidine
Basic (pKa: 10-11)
10
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Aliphatic amines are...
either surrounded by a hydrogen or a saturated carbon. The number of saturated carbons attached to the nitrogen determines the classification. (2>1>3) basic