bloodstream infections

bacteria causing bloodstream infections

GPC cause the most common infections. usually colonize skin, oropharynx, and GI tract

fungi causing bloodstream infections

candida spp cause the most common infections. presence of fungemia usually represents infection elsewhere

parasites causing bloodstream infections

eukaryotic parasites may be transiently found. malarial parasites invade both blood & hepatic cells

viruses causing bloodstream infections

preferentially infect RBCs: EBV, cytomegalovirus (CMV), HIV

transient bacteremia

flora usually introduced to blood as a result of manipulation of infected tissue or surgery involving nonsterile sites. immune system clears bacteria from bloodstream

continuous bacteremia

organisms released into bloodstream at constant rate like in endocarditis

intermittent bacteremia

periodic release of bacteria in bloodstream. organisms may be found in bloodstream early in patients with meningitis, pneumonia, pyogenic arthritis, asteomyelitis

infective endocarditis

intravascular infection. bacteria transiently enter bloodstream and attach to damaged surface of endothelium. web of cells, fibrin, and organism referred as vegetation

mycotic aneurysm

infection causes inflammatory damage and weakens arterial wall. arterial wall bulges and ruptures. causative agents similar to those that cause endocarditis