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Difference between the presentation of CMV and Mono
Mono has lymphadenopathy and pharyngitis, CMV usually does not
At risk populations for CMV
Immunocompromised patients (organ transplant)
Neonates (C of TORCH)
Risks of CMV
Other organ system involvement
CMV treatment
Ganciclovir (or another -ciclovir)
Fever+Lymphadenopathy+pharyngitis
Epstein-Barr virus/ Mono
Patient presenting with a maculopapular rash after taking antibiotics
Likely Epstein-Barr Virus (Mono)
(patient was likely prescribed them for suspected strep throat)
Pathogen of EBV/Mono
Herpes 4
Risk of EBV/Mono, and counseling
Splenic rupture (from enlargement→trauma)
limit activity
Treatment of EBV/Mono
None; it’s self-limiting
Testing options for EBV/Mono
CBC with a smear (shows atypical lymphs)
Monospot (finger poke rapid test, high rate of false negatives)
gray membrane in throat. Low fever, cervical lymphadenopathy ("Bull neck")
Diptheria
Pathogen of diptheria
Diptheria (gram+)
Risks of diptheria
Chronic skin ulcers
Testing of diptheria
Cultures from the grey membrane or skin ulcers (PCR to determine if its toxigenic or not)
Treatment of Diptheria
Macrolide or PCN (along with antitoxin, if it's toxigenic)
Antibiotics if it’s solely cutaneous
Treatment of the close contacts of a diptheria patient
Erythromycin
Dysphagia, Drooling, Distress. Sore throat with pain out of proportion to exam
Epiglottitis
Epiglottitis pathogen
Haemophilus influ B (HIB vaccine)
Epiglottitis testing
Neck x-ray or CT (usually not done, out of urgency, though)
Epiglottitis treatments
SECURE AIRWAY
Ceftriax or Vanco (± Antipyretics)
no steroids (not useful)
Cough, rhinorrhea, pink eye, headache, rash. Condition and pathogen
Viral acute pharyngitis
acute, fever, tonsil exudate, scarlet fevers. No cough, no rhinorrhea. Condition and pathogen
Group A strep Acute pharyngitis
Risks of Group A strep Acute Pharyngitis
Post strep glomerulonephritis
Treatment for Acute Pharyngitis
Viral: fluids and rest
Strep: Penicillin (erythro as back-up)
Testing of Acute Pharyngitis
McIsaac score to determine whether to test
RADT or NAAT (both POC tests),
and in kids, culture if the POC is negative
Notable DDx of acute pharyngitis
Gonorrhea
3-7 days of sore throat and hoarseness
Laryngitis
Can’t-miss DDX of Laryngitis
Laryngeal cancer (Esp in smoking)
Sore throat/swallowing, drooling, trismus, "hot potato" voice, bilateral pain that then worsens and becomes unilateral. Uvular deviation on exam
Peritonsillar abscess
Causes/pathogens of peritonsillar abscess
Acute tonsillitis, Mono, or Group A Strep
Peritonsillar abscess testing
X-ray, CT, intraoral Ultrasound, culture if aspirate is purulent
Treatment of peritonsillar abscess
Drain with needle aspiration (make needle short; could puncture carotid)
Antibiotics (augmentin or Clinda, cover anaerobes), Dexamethasone
Trismus, swelling below mandible, bulging of pharyngeal wall, systemic sx (fever or rigors)
Deep neck space infections
Potential spaces of Deep Neck Space infections
Superficial, pretrachial, or prevertebral spaces
Risks of Deep Neck Space Infections
Sepsis traveling into the chest
Deep neck space infection treatments
Aspiration or surgical drainage, broad spectrum antibiotics (Vanco)
Purulent discharge, facial pain/pressure (especially with sinus percussion), congestion
Sinusitis
Difference between viral and bacterial Sinusitis
Viral resolves within 10d
vs
Bacterial lasts longer than 10d, double-worsening pattern (start to feel better, then feel worse), high fever, or facial pain at the very start
Acute bacterial sinusitis pathogens
strep, H Flu, Moraxella
Risks of sinusitis
Preseptal cellulitis, orbital cellulitis, subperiosteal or intracranial abscess, meningitis, septic cavernous sinus thrombosis, osteomyelitis
Treatment of viral or bacterial sinusitis
Viral: supportive (rinses, flonase/inhaled steroids, anticholinergic, oral decongestant)
Bacterial: after a few days of watchful waiting, amoxicillin, augmentin, or cef or doxy
No macrolide, no bactrim
BOTH are often self-limiting; watch for improvement after diagnosis before prescribing antibiotics
What does Rinne positive mean?
AC>BC (normal)
Swelling (hematoma) of the auricle after trauma
Traumatic aricular hematoma
Traumatic aricular hematoma treatment
incision&drainage with compression dressing
Painful red ear, often around a cut/scrape/piercing
Perichondritis
Perichondritis tx
antibiotics, maybe incision and drainage
Cerumen impaction tx
Debrox (detergent ear drops) and irrigation
Foreign bodies in ear tx
Mechanical removal or aqueous irrigation
Mineral oil to dislodge insect grip
erythema and edema of the ear canal, purulent exudate
tragus and pinna tender
Otitis externa
Otitis externa pathogens
Pseudomonas or fungi (no purulence)
risks of otitis externa
Osteomyelitis of skull base (malignant otitis externa)
diabetic/immunocompromised patients
Otitis externa treatment
ofloxacin drops (for pseudomonas or staph)
Malignant otitis externa treatment
ciprofloxacin, surgical skull debridement
Edematous, persistent foul aural discharge, granulations in ear canal, deep otalgia, progressive palsies of the cranial nerves
Osteomyelitis of the base of the skull (seen on CT)
Malignant otitis externa
TM retraction, aural "fullness", fluctuating hearing, popping with swallowing/yawning
Eustachian tube dysfunction
risks of Eustachian tube dysfunction
serous otitis media, barotrauma
treatments for eustachian tube dysfunction
decongestants, and if allergic, nasal corticosteroids
TM perforation treatment to AVOID
-mycins as ear drops
new otorrhea without otitis externa (through perforation)
moderate-to-severe TM bulging
mild TM bulging+recent onset pain or intense erythema
otalgia, hearing loss, otorrhea, pruritis, fever, nausea, URI
Acute Otitis media (purulent)
pathogens of Acute Otitis media (purulent)
Bacterial (strep pneuminae, h flu, moraxella)
Nonbacterial (viral)
Treatment of purulent acute otitis media
over 6mo& at risk, or over 2yo with severe sx: 10d amoxicillin or augmentin (+ probiotics to prevent GI sfx)
If TM tubes, use fluoroquinolone
if more than 4 infections in a year, ENT referral
Tx of serous acute otitis media
Decongestants (treat eustachian tube dysfunction
asymptomatic, maybe hearing loss, no inflammation, serous middle ear fluid
serous acute otitis media
Can be asymptomatic
Tenderness, erythema, swelling, fluctuation behind the ear
Ear discharge, pain, hearing loss
Lethargy, fever, and nausea
Bulging TM, middle ear effusion, perforation; Normal appearing TM generally excludes this condition
mastoiditis
Common pathogen of mastoiditis
Pseudomonas
Epitympanic retraction pocket or a marginal
tympanic membrane perforation that exudes keratin debris or
granulation tissue
Cholesteatoma
crusty, dusty lid margins
Blepharitis
Stye-acute tender localized eyelid lesion
Hordeolum
Hordeolum pathogen
Staph
Firm chronic eyelid nodule (may result from a stye)
Chalazion
Eyelid turned in
Entropion
Eyelid turned out
Ectropion
Inflammation of lacrimal glad (swelling of upper outer eyelid)
Dacryoadenitis
Infection/inflammation of the lacrimal sac (lower, inner side of eye)
Dacryocystitis
Dacryoadenitis vs Dacryocystitis
Adenitis-gland (right under eyebrow)
Cystitis-sac (next to nose)
Treatment for Dacrocystitis
Antibiotics
Obstruction of tear drainage system (tear overflow, mucoid discharge)
Dacryostenosis
Dacryocystosis vs Dacryostenosis
cystosis: swelling, etc
stenosis: tear overflow
Dry eye (leading to red, inflamed eye)
Keratoconjunctivitis Sicca
Most common cause of Keratoconjunctivitis Sicca
autoimmune disease
Benign triangular growth extending towards the cornea
Pterygium
Pterygium risk factors
UV exposure, wind, dust, dryness
Infection of the cornea (corneal clouding, photophobia, red eye)
Infectious keratosis
Diagnosis of Infectious Keratitis
Slit-lamp, fluorescin, ±corneal scraping for culture
Most common pathogen of infectious keratosis+ treatment
HSV; -ciclovir
Treatments for infectious keratitis
Bacterial: Fluoroquinolone
HSV: -ciclovir
Fungal: Natamycin
Contact lens user with a painful red eye. Corneal infiltrate/opacity
Bacterial infectious keratitis
Pathogen of herpetic keratitis
Herpes Simplex Virus in trigeminal nerve
Corneal opacity or scarring, dendritic corneal ulcer, unilateral eye pain/redness
Herpetic Keratitis
Photophobia, small or irregular pupil, cells/flare on slit lamp
Anterior Uveitis/Iritis
Treatment of Anterior Uveitis/Iritis
Corticosteroids
Very painful red eye; severe, deep pain worsened when eye moves
Scleritis
Gradual loss of peripheral vision
Chronic Open-angle Glaucoma
Nausea/headaches, halos around light, abnormal pupil, cloudy cornea, high IOP
acute closed-angle glaucoma
Diagnosis and treatment of acute closed-angle glaucoma
Elevated IOP
topical beta-blockers or alpha-2 agonists
laser peripheral iridotomy, once possible
Painless peripheral vision loss with optic-disk cupping
Chronic open-angle glaucoma
Chronic open-angle glaucoma treatments
Prostaglandin-analog eye drops
Selective laser trabeculoplasty
Recent eye surgery+vision loss+hypopyon
Endopthalmitis
White area in iris; WBC in anterior chamber
Hypopyon
Endopthalmitis treatments
intravitreal antibiotics (vanco+ceftrazidime)