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when understanding disease and illness, what two groups do we break disease into?
communicable and chronic
Communicable disease definition
transmitted
Chronic disease definition
caused by a myriad of factors (multiple and long lasting), non-transmissible
How we “won” public health?
immunization, antibiotics, purification of water, proper disposal of sewage, pasteurization of milk, improved nutrition and personal hygiene
Step 1 of Chain of Causation
microorganism
What are examples of microorganisms?
Bacteria, virus, fungus, and parasite
Step 2 of Chain of Causation
reservoir/source
Example of reservoir/source
habitat for organism (humans, animals, air, food, water, equipment)
Step 3 of Chain of Causation
port of exit
Example of port of exit
secretions (saliva, urine, feces)
Step 4 of Chain of Causation
modes of transport
Example of modes of transport
contact, droplet, airborne, vector, fomites
Step 5 of Chain of Causation
port of entry
Example of port of entry
mucosa lining, open wound, oral, respiratory tract, urinary tract
Step 6 of Chain of Causation
susceptible host
Example of susceptible host
very young, elderly, those with chronic diseases, malnourished, immunocompromised
Examples of how to break the chain
kill pathogen, eliminate reservoir, prevent transmission (hand washing and quarantine), condoms, increases resistance in host
Examples of how to increase resistance in host
vaccines, increase vitamin A to help prevent measles
Two Examples of Bacteria
tuberculosis and tetanus
Two Examples of Viruses
smallpox and hepatitis
Two Examples of Parasites
malaria and giardiasis
Transmission Examples
directly from person to person, aerosol, contaminated object, sexual contact, vectors, carriers, fecal-oral route
Drawbacks of Vaccines
could harm indivudlas with specific illness (Guillain-Barré syndrome)
Controversy of Vaccines
religious beliefs
Ro
reproductive rate for every 1 person that is infected
Formula for calculating herd immunity
1-(1/Ro)= percentage of people who have to get vaccinated to achieve herd immunity
Elimination Status Definition
cases dont exceed endemic rates
Examples of Chronic Disease
cardiovascular disease, hypertension, cancer, diabetes
What kind of prevention is important in chronic disease?
secondary prevention (screening)
What kind of subjects are chronic disease studies done on?
animals, mice mostly for ethical reasons (PETA) and similar DNA
Which density proteins are good to have a lot of in cholesterol screening?
high density protein
Hypertension Definition
high blood pressure (normal is 120/80)
Cancer Definition
category of disease, DNA mutation of cells in an uncontrollable fashion
What does Hep B cause?
liver cancer
How to prevent Hep B?
vaccinate
Type 1 Diabetes Definition
juvenile diabetes, genetic, (body doesn’t produce insulin), amputations are common for untreated (lack of healthcare access)
Type 2 Diabetes Definition
pancreas produces insulin but the body is insulin resistant, later onset
What type of prevention is important for type 2 diabetes prevention?
secondary prevention, screening, medication for pre diabetics to prevent actual onset of diabetes (glp-1)
Genetic Disease Definition
caused by DNA mutation, 1 or 2 copies to pass on
Examples of Genetic Markers
BRCA1 and BRCA 2 (breast cancer and uterine cancer)
What is the secondary measure in the process of BRCA?
screening
What is the tertiary measure in BRCA?
prophylactic mastectomy
Another example of genetic disease
sickle cell disease (now can screen embryos)