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Epidermis
it is keratinized stratified squamous epithelium that contains four distinct cells: Keratinocytes, melanocytes, tactile epithelial cells and dendritic cells.
Primary function of the skin
Protection: Skin cushions and insulates the deeper body organs and protects the body from bumps, scrapes, and cuts.
Body temperature regulation: the skin’s rich capillary networks and sweat glands regulate the loss of heat from the body, helping to control body temperatures
Excretion: The skin acts as a miniature excretory system when urea, salts, and water are lost through sweat.
Production of Vitamin: The epidermal cells use UV radiation to synthesize vitamin D, a molecule necessary for absorbing calcium from the digestive tract
Sensory reception: The skin contains sense organs called sensory receptors that are associated with nerve endings.
Name the five principles function of the skin
Protection, body temperature regulation, excretion, production of vitamin D, sensory reception.
stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale.
Epidermis is divided into five layer, name them
Keratinocytes
the most abundant epidermal cell, produce keratin, a tough fibrous protein that gives the epidermis its protective properties.
35 to 45 days—the average time from the birth of a keratinocyte to its final wearing away.
stratum basale
the deepest epidermal layer, is firmly attached to the underlying dermis along a wavy borderline. it consists of a single row of cells, mostly stem cells representing the youngest keratinocytes
stratum spinosum
is several cell layers thick (Figure 5.3). Mitosis occurs here, but less often than in the basale layer. Dendritic cells are found in here
stratum granulosum
thin layer consists of one to five layers of flattened keratinocytes. Along with abundant pre-keratin intermediate filaments, these cells also contain keratohyalin granules and lamellar granules
stratum lucidum
occurs in thick skin but not in thin skin.
stratum corneum
The most external part of the epidermis, it is many cells thick. It is much thicker in thick skin than in thin skin
Dendritic cells
These star-shaped cells are part of the immune system.
Melanocytes
Make the dark skin pigment melanin. Found in the stratum basale
Tactile epithelial cells, or Merkel
cells, are distributed sparsely among the keratinocytes.
Keratinocytes
found in every layer of the epidermis.
The dermis,
the second major region of the skin, is a strong, flexible connective tissue. The cells of the dermis are typical of any connective tissue proper: fibroblasts, macrophages, mast cells, and scattered white blood cells
The dermis has two regions:
the papillary dermis and the reticular dermis
The papillary dermis
the superficial 20% of the dermis, is areolar connective tissue, containing very thin collagen and elastic fibers. includes dermal papillae
Dermal papillae
fingerlike projections that extend into the overlying epidermis. helps to gas diffusion and to nourish the epithelial tissue.
Reticular dermis
accounts for about 80% of the thickness of the dermis, is dense irregular connective tissue.
dermal plexus
Blood vessel that nourish the hypodermis and deeper dermis
subpapillary plexus
Blood vessels supplying the superficial dermis and epidermis
Subcutaneous
hypodermis or superficial fascia. The subcutaneous tissue consists of both areolar and adipose connective tissue, but adipose tissue normally predominates.
Melanin, Carotene, Hemoglobin
skin colors
Skin appendages
Nails, hair, hair follicles sebaceous glands, sweat glands
Nail matrix
the actively growing part of the nail
hair
is a flexible strand made of dead cells filled with hard keratin
nail
is a scalelike modification of the epidermis that corresponds to the hoof or claw of other mammals
hair follicles
are tubular invaginations of the epidermis from which the hairs grow.
shaft
the part that projects above the skin surface
root
The chief parts of a hair are
Medulla
consists of large cells and air spaces.
cuticle
is a single layer of fattened, overlapping cells, and it prevents hair from matting
Hair follicles
extend from the epidermal surface into the dermis.
hair bulb
A knot of sensory nerve endings wraps around each hair bulb to form a hair follicle receptor or root hair plexus
Sebaceous gland
skin’s oil glands and they produce sebum
Sweat glands
sudoriferous glands, we have two Eccrine gland and Apocrine gland
Eccrine glands
are by far the more numerous type. They are most abundant on the palms, soles, and forehead.
Apocrine glands
are mostly confined to the axillary, anal, and genital areas. They are larger than eccrine glands, and their ducts open into hair follicles. They produce fatty and protein substance that when decomposed it release body odors.
Sodium, ammonia, water, uric acid, and no amino acid
components sweat glands secreted by eccrine glands includes
Holocrine secretion
sebaceous gland go in a process
Mole
what structure is formed when clusters of melanocytes are transformed into melanin-containing cells (nervus cells)
Stratum granulosum
In what location can the epidermal cell type or structure keratohyalin be found
Keratinocytes, dendritic, pre-keratin cells
Stratum spinosum contains all this cells
Hypodermis is made of
Areolar connective tissue and adipose connective tissue
Melanocytes
respond to ultraviolet radiation by increasing the production of melanin