ORGO 3 Exam 3 material

What should you do in this case?

Use LDA for a specific product

What’s a requirement for the aldor condensation reaction to occur? What happens if this requirement isn’t met?

A alpha hydrogen is needed, if not hydrates form

When is heat not necessary in an aldor reaction?

When the product form is heavily conjugated

Using the acetone example, where hydrates and aldor products form, why is the aldor reaction the major product?

Acid-base chemistry occurs faster than nucleophilic addition

What drives the alpha-beta-unsaturated carbonyl product in aldol reaction?

Heat, it’s what removes h2o