Precocious Puberty

Precocious puberty is pubertal development before —

the age of 8

Delayed puberty is described as absent or incomplete breast development after —

the age of 12

The diagnosis of precocious puberty typically constitutes an endocrinologic workup to evaluate —

gonadotropin levels

— is associated with intracranial tumors or may simply be idiopathic

True precocious puberty

Pseudoprecocious puberty, also referred to as —

peripheral pseudosexual precocity or gonadotropin-independent precocious puberty

Pseudoprecocious puberty has been linked with —

ovarian, adrenal, and liver tumors

The uterus may appear —

enlarged with a postpubertal shape and contain a prominent endometrial stripe

Isosexual precocity

Early development of secondary sexual characteristics with menses, ovulation, and elevated gonadotropin levels

Premature adrenarche

Characterized by isolated pubic hair development and increased levels of adrenal androgens

Premature thelarche

Characterized by isolated breast development with normal prepubertal hormones

Secondary sexual characteristics

Body changes typically occurring at puberty such as enlargement of breasts and growth of pubic hair

Virilization

A condition in which a female develops physical changes that are associated with males hormones (androgens) such as hair growth