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Flashcards based on lecture notes about disrupted homeostasis.
Diffusion
Movement of solutes from an area of greater concentration to an area of lesser concentration.
Osmosis
Movement of water from a dilute solution (low concentration of solute) to a more concentrated solution (high concentration of solute).
Filtration
Hydrostatic pressure overcoming the opposing osmotic pressure.
Fluid Volume Deficit (FVD)
A negative fluid balance leading to dehydration and volume depletion.
Fluid Volume Excess (FVE)
An excess of fluid in the body, potentially due to heart failure, liver cirrhosis, kidney disease, or IV therapy.
Physiologic Fluid Loss
A risk factor for FVD, including GI losses, burns, excessive sweating, and third-spacing.
Cardiac, Liver, Renal, and Endocrine Disorders
Conditions that can lead to fluid volume excess.
Cerebral Hypoperfusion
A potential impact of FVD, leading to organ and tissue damage.
Polydipsia
Excessive thirst, a potential impact of FVE.
Hypernatremia
A sodium imbalance characterized by hypertonic sodium gain, pure water loss, or hypotonic fluid loss.
Hyponatremia
A sodium imbalance that can be hypovolemic, euvolemic, or hypervolemic.
Hypertonic Sodium Gain
A cause of hypernatremia.
Hypovolemic Hyponatremia
Low sodium levels associated with low blood volume.
Euvolemic Hyponatremia
Low sodium levels with normal blood volume.
Hypervolemic Hyponatremia
Low sodium levels associated with high blood volume.
Neurological Symptoms (Hypernatremia)
A clinical presentation of hypernatremia.
Acute Hyponatremia
A medical emergency.
Chronic Hyponatremia
May be asymptomatic.
IV and Oral Fluid Replacement
Nursing intervention for hypernatremia.
Fluid Restriction
Possible intervention for normovolemic hypotonic hyponatremia.
Hypokalemia
A potassium imbalance potentially caused by aldosterone release, GI losses, poor dietary intake, or non-potassium sparing diuretics.
Hyperkalemia
A potassium imbalance potentially caused by potassium shift to extracellular space, metabolic acidosis, cellular damage, or kidney disease.
Aldosterone Release
A potential cause of hypokalemia.
Metabolic Acidosis
A potential cause of hyperkalemia.
Renal Insufficiency
A risk factor for hyperkalemia.
Gastrointestinal Symptoms (Hypokalemia)
Clinical presentation of hypokalemia when potassium is less than 3mEq/L.
Cardiovascular Impact (Hyperkalemia)
A significant concern with hyperkalemia.
Potassium Binders
Medications used to reduce potassium levels.
Cardiac Monitoring
Important nursing action for hyperkalemia.
Hypomagnesemia
A magnesium imbalance caused by poor intake/absorption, kidney disease.
Hypermagnesemia
An uncommon, but potentially fatal magnesium imbalance causing cardiac and neurologic dysfunction.
Phytic Acid, PPIs, Calcium, Phosphates, and Fats
Substances that inhibit magnesium absorption.
Cardiac Dysrhythmias
A potential consequence of hypomagnesemia.
Laxatives, Antacids, Supplements
Potential causes of hypermagnesemia.
Renal Insufficiency
Increases susceptibility to hypermagnesemia.
Magnesium Toxicity
A concern during magnesium supplementation.
Hypocalcemia
A calcium imbalance caused by decreased parathyroid hormone, hypomagnesemia, alkalosis, or low vitamin D.
Hypercalcemia
A calcium imbalance caused by excessive parathyroid hormone, malignancy, or hypervitaminosis D.
Decreased Parathyroid Hormone
Can cause hypocalcemia.
Excessive Parathyroid Hormone
Can cause hypercalcemia.
Renal Failure
A prevalent cause of hypocalcemia.
Hyperparathyroidism
A potential cause of hypercalcemia.
Tetany
A clinical presentation of hypocalcemia characterized by positive Chvostek’s and Trousseau’s sign.
Encephalitis
Possible with hypercalcemia at levels greater than 14 mg/dL.
Calcium and Vitamin D Supplementation
Encouraged for hypocalcemia.
Physical Activity and Hydration
Encouraged for hypercalcemia.
Metabolic Acidosis
Serum bicarbonate decreased and pH below 7.35.
Metabolic Alkalosis
Serum bicarbonate increased and pH above 7.45.
Renal and GI Loss of Bicarbonate
Can cause Metabolic Acidosis.
Renal and GI Loss of Hydrogen Ions
Can cause Metabolic Alkalosis.
Salicylates, Iron, Metformin
Medications that can cause metabolic acidosis.
Vomiting, Gastric Suction
Can cause a loss of gastric hydrogen ions, leading to metabolic alkalosis.
Osteoporosis, Worsening Kidney Disease
Complications of metabolic acidosis.
Confusion, Lethargy
Symptoms associated with metabolic acidosis.
Hypoventilation
A clinical presentation of metabolic alkalosis.
Respiratory Acidosis
Serum carbon dioxide increased and pH below 7.35.
Respiratory Alkalosis
Serum carbon dioxide decreased and pH above 7.45.
Hypoventilation
Can lead to respiratory acidosis.
Hyperventilation
Can lead to respiratory alkalosis.
Drugs, Neurologic Disorders, Pneumonia, Asthma, Stroke, Surgery
Acute processes causing retention of CO2, leading to respiratory acidosis.
Hypoxemia
Can cause hyperventilation, leading to respiratory alkalosis.
Memory Loss, Poor Coordination
Can occur with chronic respiratory acidosis.
Shortness of Breath, Dyspnea, Orthopnea, Wheezing
Clinical presentations of respiratory alkalosis.
Cyanosis, Increased ICP
Clinical presentation of respiratory acidosis.
Tripod Position
A common posture for clients with COPD and respiratory acidosis.
COPD
Chronic Obstructive Pulmonary Disease.
Intracellular Fluid (ICF)
Fluid located inside the cells; makes up 2/3 of total body fluid.
Extracellular Fluid (ECF)
Fluid located outside the cells; makes up 1/3 of total body fluid.
Interstitial Fluid
The main component of the ECF lying between cells.
Plasma
The fluid component of blood, part of the ECF.
Solute
A substance dissolved in a solution.
Hydrostatic Pressure
The pressure exerted by a fluid against a surface.
Osmotic Pressure
The pressure needed to prevent the movement of water across a semipermeable membrane.
Dehydration
A state of decreased water volume in the body.
Third-Spacing
The accumulation and sequestration of trapped extracellular fluid in an actual or potential body space as a result of disease or injury.
Morbidity
The condition of being diseased.
Hypoperfusion
Reduced blood flow.
Electrolyte
A mineral salt dissolved in body fluid.
Hypertonic
Having a higher osmotic pressure than another fluid.
Hypotonic
Having a lower osmotic pressure than another fluid.
SIADH
Syndrome of Inappropriate Antidiuretic Hormone secretion.
Dextrose
A simple sugar; glucose.
Comorbidity
The presence of two or more diseases or conditions at the same time in one person.
Rhabdomyolysis
The breakdown of muscle tissue that releases a damaging protein into the blood.
Creatinine Clearance
A measure of kidney function.
Delirium
A serious disturbance in mental abilities that results in confused thinking and reduced awareness of the environment.
Myocardial Infarction
Heart Attack.
Hyperparathyroidism
Overactivity of the parathyroid glands resulting in excess production of parathyroid hormone.
Hypothyroidism
Underactivity of the thyroid gland.
Hypervitaminosis D
An abnormally high level of vitamin D.
Osteoporosis
A condition in which bones become weak and brittle.
Thyroidectomy
Surgical removal of the thyroid gland.
Parathyroidectomy
Surgical removal of the parathyroid gland.
Renal Calculi
Kidney Stones.
Paresthesia
An abnormal sensation, typically tingling or pricking ('pins and needles').
Tetany
A condition marked by intermittent muscular spasms, caused by malfunction of the parathyroid glands and a consequent deficiency of calcium.
DKA
Diabetic Ketoacidosis.
Lethargy
A state of sluggishness, inactivity, and apathy.
Tachydysrhythmias
An abnormally rapid heart rhythm.
Hyperaldosteronism
A condition in which the adrenal glands produce too much aldosterone, which can lead to hypertension and low potassium levels.