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gly step 1 enzyme
hexokinase
gly step 2 enzyme
phosphohexose isomerase
gly step 3 enzyme
PFK1 (phosphofructokinase1)
gly step 4 enzyme
aldolase
gly step 5 enzyme
triose phosphate isomerase
gly step 6 enzyme
GAPDH (glyeraldehyde-3-phosphate-dehydrogenase)
gly step 7 enzyme
phosphoglycerate kinase
gly step 8 enzyme
phosphoglycerate mutase
gly step 9 enzyme
enolase
gly step 10 enzyme
pyruvate kinase
gly step 1 stuff
phosphorlyation of glucose; traps glucose in the cell
gly step 2 stuff
isomerization to F6P; aldose to ketose; prep to cleave
gly step 3 stuff
second phosphorylation; IRREVERSIBLE; makes it more symmetrical
gly step 4 stuff
cleavage of F16BP; aldehyde & ketone created
gly step 5 stuff
triose phosphate isomerzation; end of prep phase; creates 2 equivalents of aldehyde
gly step 6 stuff
oxidation & phosphorylation of G3P; NAD+ → NADH (reduced); unfavorable rxn; x2; phosphate group comes from environment
gly step 7 stuff
phosphoryl transfer; really favorable rxn; generates ATP through substrate-level phosphorylation (1st one)
gly step 8 stuff
rearrangement; prep for intermediate in next step; from 3rd C to 2nd C - OH
gly step 9 stuff
dehydration of phosphoenol pyruvate; makes enol phosphate (unstable); take away H2O for double bond
gly step 10 stuff
pyruvate formation & substrate-level phosphorylation; yields 2 ATP w/ substrate-level phosphorylation
gly step 1 react
glucose
gly step 2 react
G6P (glucose-6-phosphate)
gly step 3 react
F6P (fructose-6-phosphate)
gly step 4 react
F16BP (fructose-1,6-bisphosphate)
gly step 5 react
DHAP (dihydroacetone phosphate)
gly step 6 react
G3P (glyceraldehyde-3-phosphate)
gly step 7 react
1,3-BPG (1,3-bisphosphoglycerate)
gly step 8 react
3-PG (3-phosphoglycerate)
gly step 9 react
2-PG (2-phosphoglycerate)
gly step 10 react
phosphoenolpyruvate
gly step 1 pro
G6P (glucose-6-phosphate)
gly step 2 pro
F6P (fructose-6-phosphate)`
gly step 3 pro
F16BP (fructose-1,6-biosphosphate)`
gly step 4 pro
G3P & DHAP (glyceraldehyde-3-phosphate & dihydroxyacetone phosphate)
gly step 5 pro
G3P (glyceraldehyde-3-phosphate)`
gly step 6 pro
13BPG (1,3-bisphosphoglycerate)`
gly step 7 pro
3PG (3-phosphoglycerate)`
gly step 8 pro
2PG (2-phosphoglycerate)`
gly step 9 pro
phosphoenolpyruvate
gly step 10 pro
pyruvate
ADP → ATP steps
7 & 10
NAD+ → NADH
6
ATP → ADP
1 & 3
irreversible steps
1, 3, 10