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Interventions for mania other than initiating medication
Stop antidepressant if taking
Check for lifestyle influences, like SUD
First-line for mania
Lithium or valproate or SGA
or
Lithium or valproate, + SGA
What BPD drug can be added to a mania regimen for acute agitation?
Benzodiazepine
Second-line for mania
Carbamazepine
Or
Lithium + valproate
First-line for bipolar depression
Any of these options (“or”)
Lithium
Quetiapine
Lamotrigine — Smithgall likes this one
Cariprazine
Lurasidone
Second-line for bipolar depression
Any of these options (“or”)
Valproate
Lumapeterone
Olanzapine + fluoxetine
For refractory or psychotic depression
ECT