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Heart function
Pumps blood throughout body
Right atrium
Receives oxygen‑poor blood from body
Lungs
Site of gas exchange; oxygenates blood
Aorta
Main artery delivering oxygenated blood to body
Heart energy consumption
~6 kg ATP per day
Heart blood volume pumped
~2,000 gallons per day
Heart metabolism
Primarily fatty acids and glucose
Pacemaker cells
Generate rhythmic electrical impulses
SA node location
Wall of right atrium near superior vena cava
SA node function
Primary pacemaker; ~100 depolarizations per minute
Resting heart rate
~70 bpm due to autonomic modulation
Cardiac contraction
Requires extracellular Ca2+ and SR Ca2+
Heart valves
Control blood flow direction
Valve defects
Regurgitation, stenosis, myxomatous degeneration
Myxomatous valves
Excess proteoglycans → floppy valves