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Harmonic Imaging
The creation of an image from sound reflections at twice the frequency of the transmitted sound
Fundamental Frequency
Transmitted Frequency
nonlinear behavior
Harmonic frequency sound arises from ________________ _______________
tissue harmonics and contrast harmonics
Two important forms of harmonics
by processing reflections that are twice the fundamental frequency
How is a harmonic image created?
in an even or symmetrical manner
Linear systems respond how?
unevenly or asymmetrically
A system is considered non-linear when it behaves ______________
compressions and rarefactions of the sound beam
What creates the nonlinear speed variation that causes harmonic imaging?
the sound beam is very strong, the many different superficial anatomic layers distort the sound beam
List the 2 reasons that artifacts arise within the first few cm of tissue
because they do not exist at superficial depths
Why can harmonic signals not distort?
Non-linear
Describe the relationship between tissue harmonics and sound beam strength
-None
-only a tiny amount
-significant amount
What amount of tissue harmonics are created by
-Weak sound beams
-intermediate strength sound beams
-strong sound beams
Least Likely
The Beams that are most likely to create harmonics are also ________ __________ to create artifacts
Not present
Tissue harmonics are ___________________ as sound leaves the transducer
in the tissue during transmission
Where are tissue harmonics created?
Pulse inversion harmonics
This technique is specifically designed to utilize harmonic reflections which are distortion free while eliminating distorted fundamental reflections
Harmonic imaging
This type of imaging creates images only from the harmonic.
Pulse inversion harmonics
Two consecutive pulses transmitted down each scan line with the second pulse being an inverted copy that is out of phase with the first pulse describes
Double the pulses are needed to create an image
time frame is doubled
frame rate is halved
temporal resolution is reduced
What are the disadvantages of pulse inversion harmonics?
Power modulation harmonic imaging
Two consecutive pulses are transmitted down each scan line with the second pulse being double the strength of the first pulse.
Double the pulses
frame rate is halved
temporal resolution is reduced
What are the disadvantages of power modulation harmonic imaging?
microbubbles
Another name for contrast agents
-safe
-metabolically inert
-long lasting
-strong reflector of ultrasound
-small enough to pass through capillaries
What five requirements must contrast agents meet?
contrast agents
Designed to create strong reflections that "light up" blood chambers and vessels
generates much stronger harmonics
What effect do contrast agents have on tissue harmonics?
because microbubbles act in a non-linear manner when struck by sound
Why do contrast agents increase the harmonics?
compressions and rarefactions
A sound wave is an oscillation of pressure or a series of _________________ and _________________
grows and shrinks
When a microbubble is within a sound beam, the bubble __________ and _________ in relation to pressure changes
resonance
The uneven behavior of bubble size when exposed to sound
expand to a greater extent than they shrink
Bubbles ___________ to a greater extent than they ___________
Peak rarefaction pressure
___________ __________ pressure is the most important with regard to contrast harmonics
rarefaction expands, compression shrinks
Rarefaction pressure ______________ the bubble, while compression pressure ____________ the bubble
the measurement of the amount of contrast harmonics produced
What is the mechanical Index?
-lower frequency sound
-stronger sound waves
The numerical value of the MI increases with
>1.0
Beams must have a MI of _______ to create substantial harmonic signals
-no harmonics
-backscatter
-linear behavior
-higher frequency sound
-low beam strength
-bubble expands very little
Low MI < 0.1
-some harmonics
-resonance
-nonlinear behavior
-lower frequency sound
-higher beam strength
-bubble expands more moderately
Higher MI 0.1 - 1.0
-strongest harmonics
-bubble disruption
-extreme non linear behavior
-lowest frequency sound
-highest beam strength
-bubble expands greatly
Highest MI >1.0
-the nature of the outer shell
-the gas that fills the microbubble
What are the 2 important characteristics of contrast agents
the relationship between the shell and the internally trapped gas
What determines the contrast agents stability and longevity while circulating in the blood?
wide-bandwidth or broadband
Pulse inversion harmonics uses ___________________ transducers
transmission, reflection
Tissue harmonics are created in the tissue during _________________ while contrast agent harmonics are created during _________________
sound propagates thru tissue
Tissue harmonics occur as
contrast agents are present and MI is > 0.1
contrast harmonics occur when