Biochemistry - Quiz 4,

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1
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Which of the following statements is incorrect concerning the following equilibrium?

CO2 + H2O

a) The majority of CO2 is transported to the lungs in the form of HCO3-.

b) A decrease in the partial pressure of CO2 will result in a decrease of pH.

c) ALL OF THESE are incorrect

d) This reaction is catalyzed by carbonic anhydrase.

e) The H2CO3 dissociates to H+ and bicarbonate ion, HCO3-.

b) A decrease in the partial pressure of CO2 will result in a decrease of pH.

2
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Sickle-cell anemia is caused by:

a) polymerization of hemoglobin

b) a substitution of glutamic acid residue for histidine at the C terminus of the alpha chain

c) a substitution of a glutamic acid residue for a phenylalanine residue at the beta-6 position

d) a substitution of a serine residue for a glutamic acid residue at the beta-6 position

e) a decreased production of alpha chains of hemoglobin

a) polymerization of hemoglobin

3
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Are these the same molecule? (chair vs boat conformation)

a) yes

b) no

https://extcanvas.ucsd.edu/assessment_questions/170359/files/2444006/download?verifier=mQlW5o44ilgQ8ehLg2MZhjQpIrAlMbUqzfUwXRda&wrap=1

a) yes

4
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Increasing the fraction of saturated fatty acids in a membrane would ____________ its fluidity.

a) have no effect on

b) increase

c) NONE OF THESE

d) decrease

e) maintain

d) decrease

5
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What is NOT an aspect of the Bohr effect?

a) the regulation of hemoglobin-oxygen binding by hydrogen ions

b) the regulation of hemoglobin-oxygen binding by carbon dioxide

c) NONE OF THESE are aspects of the Bohr effect

d) ALL OF THESE are aspects of the Bohr effect

e) the alteration of hemoglobin conformation during the low-oxygen stress

e) the alteration of hemoglobin conformation during low-oxygen stress

6
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Which of the following have the empirical formula CHO?

a) lipids

b) NONE OF THESE

c) carbohydrates

d) proteins

e) nucleic acids

b) NONE OF THESE

7
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Which of the following make proteins less soluble when attached?

a) ALL OF THESE

b) nucleic acid

c) NONE OF THESE

d) carbohydrates

e) lipids

e) lipids

8
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Which of the following are generally insoluble in water?

a) proteins

b) carbohydrates

c) lipids

[choose one or more options]

C only

9
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Which of the following is correct concerning hemoglobin?

a) The iron of the heme group of deoxyhemoglobin is in the Fe+2 oxidation state.

b) The diameter of the iron ion increases upon binding to oxygen.

c) The function of hemoglobin is oxygen storage in muscle.

d) The heme group is bound to the globin chain by two disulfide bonds to cysteine residues.

e) The globin chain contains an extensive beta-sheet structure.

a) The iron of the heme group of deoxyhemoglobin is in the Fe+2 oxidation state.

10
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Which of the following are important for signaling?

a) proteins

b) carbohydrates

c) lipids

[choose one or more]

ALL OF THESE

11
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Which of the following is the main component in the exoskeletons of insects?

a) proteoglycan

b) cellulose

c) starch

d) glycogen

e) glycosaminoglycan

f) protein

e) glycosaminoglycan

12
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Which of the following is NOT correct concerning the oxygenation plot of proteins X and Y, shown below?

a) Protein X exhibits tighter oxygen binding than does protein Y.

b) NONE OF THESE are incorrect

c) Protein Y could correspond to fetal hemoglobin, and protein X could correspond to normal adult hemoglobin

d) One explanation for the difference could be that protein X does not bind 2,3-BPG as well as protein Y.

e) The difference in oxygen affinity would allow oxygen to be transferred from protein Y to protein X.

https://extcanvas.ucsd.edu/assessment_questions/427924/files/4129940/download?verifier=lJqNAwv119hubrQs3fgZTWnRLOmQkNwZo2nWOvtF

c) Protein Y could correspond to fetal hemoglobin, and protein X could correspond to normal adult hemoglobin.

13
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When a lipid is attached to a protein, it usually:

a) increases enzymatic efficiency

b) makes the protein more hydrophilic

c) targets the protein to the membrane

d) provides energy for enzymatic reactions

c) targets the protein to the membrane

14
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Glucose polymerizes to form cellulose, starch, and glycogen. Which of the following is true?

a) All three contain alpha-1,6 glycosidic bonds.

b) Cellulose is the most stable of the three.

c) Humans can digest all polymers of glucose.

d) Digestion of starch requires the cellulase enzyme.

e) In cellulose and starch, glucoses are connected with beta-1.4 linkages, while glycogen uses alpha-1,4 linkages.

b) Cellulose is the most stable of the three.

15
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2,3-bisphosphoglycerate:

a) preferentially binds to oxyhemoglobin and stabilizes it.

b) NONE OF THESE

c) is present in red blood cells

d) ALL OF THESE

e) binds in the central cavity in the R form of hemoglobin.

c) is present in red blood cells.

16
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Multiple sugars linked together can form which of the following?

a) polysaccharide

b) oligosaccharide

c) complex carbohydrate

d) NONE OF THESE

e) ALL OF THESE

ALL OF THESE

17
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Which of the following play important structural roles in biology?

a) proteins

b) carbohydrates

c) lipids

[choose 1 or more]

ALL OF THESE

18
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Which of the following is correct concerning the oxygenation plot of proteins X and Y, shown below?

{Y (fraction saturation) by pO2 (torr)}

a) Protein Y corresponds to myoglobin; protein X corresponds to hemoglobin.

b) Protein X would function as a better transport protein than protein Y.

c) Protein Y contains multiple binding sites.

d) Protein Y exhibits tighter oxygen binding than protein X.

e) Protein X exhibits cooperative binding; Y does not.

c) Protein Y contains multiple binding sites.

19
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Which of the following are always at least partially hydrophobic?

a) proteins

b) carbohydrates

c) lipids

[choose 1 or more]

C only

20
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Which of the following is the basis of most of the organic matter on our planet?

a) lipids

b) proteins

c) carbohydrates

d) nucleic acids

e) small molecules

c) carbohydrates

21
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two cell types in stratum basale

merkel cells

melanocyte

22
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predominant cell type in statum spinosum

keratinocytes

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ant crals up leg

merkel cell

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layer of epidermis superficial to spinosum

stratum granulosum

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catilage template for bone rpoduction

hyaline

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connective tissue in hypodermis

areolar and adipose

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location in body for fibrocartilage

knees

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thick skin

palms and soles

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deepest part of episdermis

basale

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hair folicle gland

sebaceous

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elastic cartilage

ears and epiglottis

32
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epidermis thixk and thin

stratum lucidum is visible

papillary layer thicker