Quant Analysis Exam 2

If t calculated > t table the difference is

signifigant

pooled =

average

we always put the larger _______ in the numerator so that F ≥ 1

standard diviation

Grubbs test for bad data needs at least how many measurments

4

for acuracy use

confidence interval

for percision use

f test

Specificity (selectivity)

the ability to distinguish the analyte from other species in the sample

linearity

a measure of how well data in a graph follow a straight line

a good fit for square of correlation coefficient would be

R^2 > = 0.995 or 0.999

robustness

ability of an analytical method to be unaffected by small, deliberate changes in operating parameters

range

the concentration interval which linearity, accuracy, and percision, are all accepted

linear range

concentration range over which calibration curve is linear

dynamic range

concentration range over which there is a measurable response

calibration curve

graph of the response versus concentration of analyte

spike recovery

% recovery = C spiked sample - C unspiked sample / C added (x 100)

matrix effect

change in analytical signal caused by anything in the sample other than analyte

equalibrium

state in which the forward & reverse rates of all reactions are equal, concentrations remain constant

equalibrium constant

k = [C]^c [D]^d / [A]^a [B]^b

10^5 Pa =

1 Bar

751.8 torr =

1 Bar

confidence interval

μ = x̄ ± ts/√n

degrees of freddom

df = n - 1

Examples of method validation

selectivity, linearity, accuracy, percision, sensitivity, range