CHAPTER 23 - AMINES

Preparation of amines (23.6)

[1] Direct nucleophilic substitution with NH3

and amines (23.6A)

[2] Gabriel synthesis (23.6A)

[3] Reduction methods (23.6B)

[4] Reductive amination (23.6C)

d

Reactions of amines

[1] Reaction as a base (23.8)

[2] Nucleophilic addition to aldehydes and ketones (23.10)

With 1° amines:

[2] Nucleophilic addition to aldehydes and ketones (23.10)

With 2° amines:

3] Nucleophilic substitution with acid chlorides and anhydrides (23.10)d

[4] Hofmann elimination (23.11)

[5] Reaction with nitrous acid (23.12)

With 1° amines:

[5] Reaction with nitrous acid (23.12)

With 2° amines:

Reactions of diazonium salts

[1] Substitution reactions (23.13)

[2] Coupling to form azo compounds (23.14)