Matching Equation Terms with Definitions

Permeability coefficient

P

Diffusion coefficient

D

Partition coefficient

K

Membrane thickness

h

Flux (area-normalized rate of diffusion)

J

Concentration in the gastrointestinal (donor) compartment

CGI

Concentration in the plasma (receptor compartment)

GP

Rate of drug absorption or diffusion over time

dQ/dt

Surface area of the membrane

A

Quantity or amount of drug that has diffused across the membrane

Q

Total mass of drug that has diffused

M

A small change or differential

d

Time

t

Concentration difference between the gastrointestinal (donor) compartment and plasma (receptor) compartment

(CGI - CP)