Acid Chloride Reactions

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15 Terms

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<p>Reaction used to create Acid Chlorides from Carboxylic Acids </p>

Reaction used to create Acid Chlorides from Carboxylic Acids

SOCl2

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Acid Chlorides to Carboxylic Acid

H3O+

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<p>Friedel-Crafts acylation</p>

Friedel-Crafts acylation

AlCl3

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Acid Chlorides to Ester

ROH

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Acid Chloride to Primary Amide

NH3

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Acid Chloride to Secondary Amide

RNH2

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Acid Chloride to Tertiary Amide

R2NH

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Acid Chloride to Aldehyde

LiAlH(OtBu)3 or H2/pd-BaSaSO4/S

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Acid Chloride to Primary Alcohol

  1. LiAlH4

  2. H3O+


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Acid Chloride to Ketone

R-MgX or R-Li

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Acid Chloride to Tertiary Alcohol

  1. R-MgX or R-Li (2eq)

  2. H3O+


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Acid Chloride to Ketone

(R)2-CuLi

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Acid Chloride to Anhydride

sodium carboxylate

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Acid Chloride to Cyclic Amide

N replaces Cl

<p>N replaces Cl</p>
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<p>Acid Chloride to end primary alcohol</p>

Acid Chloride to end primary alcohol

LiAlH4