Week 2 Check Your Understanding

The most common primary immune deficiency that affects only B cells is

Selective IgA deficiency

A serious complication of deep vein thrombosis is

Pulmonary embolus

The Philadelphia chromosome is a balanced chromosome translocation that forms a new gene called

BCR-ABL

Autologous stem cell transplantation is a procedure in which

Stem cells are harvested from the patient and then returned to the same patient

Velocity of blood flow is measured in

Centimeters per second

RhoGAM would be appropriate in an Rh-_____ woman with a _____ Rh antibody titer carrying an Rh-_____ fetus

Negative; negative; positive

Which disorder is considered a primary immunodeficiency disease?

HIV/AIDS

A 5-year-old with loss of appetite, fatigue, and refusal to walk because of pain most likely has

ALL (acute lymphoblastic leukemia)

Glomerulonephritis following a recent strep throat infection is which hypersensitivity reaction?

Type III

Seasonal allergic rhinitis is most involved in type II hypersensitivity reactions

False; it is a type I hypersensitivity reaction

Burkitt lymphoma is most closely associated with

Epstein–Barr virus

An increase in blood flow to a localized area following an injury is called

Hyperemia

An important mediator of a type I hypersensitivity reaction is

Histamine

Which listed clinical finding is indicative of compartment syndrome?

Absent peripheral pulses; this is a late finding, and pulses may remain present earlier

Peripheral edema is a result of

Venous thrombosis

Clinical manifestations of chronic arterial obstruction include

Intermittent claudication

Renal insufficiency is a common complication of which disease?

Myeloma

Tissues autoregulate their rate of blood flow by controlling

Vascular resistance

The relationship of blood flow (Q), resistance (R), and pressure difference (ΔP) is expressed by

Q = ΔP/R

Severe back pain, generalized bone demineralization, compression fracture, and elevated calcium suggest

Myeloma

A newborn with melena, bleeding from the umbilicus, and hematuria most likely has

Vitamin K deficiency bleeding

The megakaryocyte is a precursor to

Platelets

Treatment for hemophilia A includes

Factor VIII replacement

Most carbon dioxide is transported in the bloodstream as

Bicarbonate ion

Heparin may be used in selected cases of disseminated intravascular coagulation to

Inhibit further clotting factor consumption

A 3-year-old boy with prolonged bleeding after minor trauma, prolonged aPTT, and a normal platelet count likely has

Hemophilia

Low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) characterize

Iron-deficiency anemia

Excessive red cell lysis can be detected by measuring serum

Bilirubin

A laboratory finding helpful in confirming iron-deficiency anemia is

Elevated total iron-binding capacity

Activated partial thromboplastin time (aPTT) assesses

The intrinsic and common coagulation pathways

An increase in hemoglobin affinity for oxygen occurs with

A shift to the left in the oxyhemoglobin dissociation curve

Which listed vessel normally demonstrates the most rapid blood flow: arteriole, capillary, venule, or vena cava?

The vena cava

Vaccination for pneumococcal pneumonia should be performed before 1 year of age in patients with sickle cell anemia

False

Dysfunction of which organ would lead to clotting factor deficiency?

Liver

The strength of the bond between oxygen and hemoglobin is known as

Oxygen–hemoglobin affinity

A deficiency of von Willebrand factor impairs

Platelet adhesion to injured tissue

Thalassemia may be confused with iron-deficiency anemia because both are

Microcytic

The movement of blood through the vascular system is opposed by

Resistance

Two serious oncology emergencies associated with non-Hodgkin lymphoma are superior vena cava obstruction and spinal cord compression

True

A commonly ingested substance associated with prolongation of bleeding time is

Aspirin