ADI W3

Benign Bone Tumours

What % of Giant Cell Tumour’s are malignant?

20%

What % of Giant Cell Tumour’s are benign?

80%

Are Giant Cell Tumours malignant, quasimalignant or benign?

Quasimalignant

What type of tumour is a Giant Cell Tumour?

A highly vascular connective tissue tumour

What % of primary malignant bone tumours do Giant Cell Tumours make up?

5%

What % of benign bone tumours do Giant Cell Tumours make up?

15%

What is the age range for Giant Cell Tumours?

20-40 years

What is the overall M:F ratio for Giant Cell Tumours?

M=F

What is the M:F ratio for benign Giant Cell Tumours?

M 2:3 F

What is the M:F ratio for malignant Giant Cell Tumours?

M 3:1 F

What are the common sites for Giant Cell Tumour’s?

• Femur (distal)

• Tibia (proximal)

• Radius (distal)

• Humerus (proximal)

Can pathological fractures occur before symptoms present in Giant Cell Tumours?

Yes, pathological fractures precipitate symptoms

→ May not be known until symptoms develop

What are the radiological features of Giant Cell Tumours?

• Epiphyseal location

• Lytic

• Expansile lesion (intact cortex=benign lesion)

• Subchondral lesion

• 40% are soap bubbly

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Distal femur

• Breach of cortex

• Wide zone of transition

• Lytic

• Escaped fatty bone marrow tissue (can see its superimposed and sitting outside of bone)

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Tibia

• Eccentrically located

• Note how it doesn’t invade the hyaline articular cartilage or cross the bone plate

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Tibia

• Eccentrically located

• Require histology to see if benign

• Epiphyseal and metaphyseal

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Tibia

• Possible loss of cortex (malignant)

• Wide zone of transition

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Fibula

• Intermediate zone of transition

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Fibula

• Broken cortex

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Radius

• Soap bubbly

• Intermediate zone of transition

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Radius

• Malignant

• Massive bone destruction

What benign bone tumour is this, where is it, and what features can be seen?

Giant Cell Tumour

• Radius

• Assume malignant until otherwise

• Expansile

• Cortex appears mostly intact

• Zone of transition