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Conduction?
Send information up and down the cord
Connects parts of the body with each other and with the brain
Sensory information goes in and motor information goes out
Neural Integration?
Spinal neurons receive multiple inputs from multiple sources and integrates that information
Generate the appropriate → output
Locomotion?
Our motions require coordination with multiple muscle groups and neurons in the brain
Neurons in the spine coordinate these circuits with → outputs
Reflexes?
Reflexes from the spine are key in:
Posture
Motor coordination
Protective responses
Spinal cord?
Cylinder of nervous tissue that arises from the brainstem at the foramen magnum of the skull
Goes as far as L1/L2 vertebrae
Spinal cord is divided into cervical, thoracic, lumbar, and sacral regions
The cord ends before the sacral region, but spinal nerves emerge from this region
Cervical enlargement?
From the C4 to T1
Upper limbs nerves emerge
Lumbosacral enlargement?
T9 to T12
Pelvic region and lower limbs nerves emerge
Cauda equina?
Roots of the lower spinal nerves that angle inferiorly (like wisps of hair)
Innervate with pelvic organs and lower limbs
Just inferior to the lumbar enlargement is the conus medullaris (medullary cone)?
Where the spinal cord terminates around L1 and L2
Coming off of the conus medullaris is the filum terminale (terminal filum)?
Anchors the spinal cord to the → coccyx
Protecting the spinal cord is essential because?
if damaged, the cord cannot be regenerated
The vertebral column and the meninges are the protective structures for the spinal cord
The spinal cord is located within the?
Located within the vertebral canal of the column
within the → vertebral foreman
Meninges?
Three protective layers of connective tissue that encircle the → spinal cord and brain
Spinal meninges?
Surround the spinal cord and are continuous with cranial meninges
Dura mater?
Most superficial (outer meninge), thick layer composed of dense irregular connective tissue
Epidural space?
Cushion of fat and connective tissue between the dura mater and vertebral → wall
Arachnoid mater?
Middle of the meninges, thin, avascular covering made up of collagen and elastic fibers
Arranged like → spider web
Subdural space?
Filled with interstitial fluid, area between the dura mater and arachnoid mater
Subarachnoid space?
Space between the arachnoid mater and pia mater
Filled with → cerebrospinal fluid (CSF)
Pia mater?
Innermost layer, made up of thin transparent connective tissue
Adheres to the surface of the → spinal cord
Vascular, contains blood vessels that supply nutrients and oxygen to the spinal cord
White matter?
Of the spinal cord contains myelinated axon bundles
Carry signals from one part of the CNS to → another
Gray matter?
Of the spinal cord is shaped like a → H or a butterfly
Consists of dendrites, cell bodies, neurons, unmyelinated axons and neuroglia
Site of information processing, synaptic → integration
Spinal Tracts?
Fibers in each tract have similar origin, destination and function
Ascending tracts?
Carry sensory information → up
Descending tracts?
Carry motor information → down
Somatic sensory pathways?
Relay information from sensory receptors to the cerebral cortex and cerebellum
Pathways to the cortex follow sets of neurons called first, second, and third-order neurons
First-order neurons?
Detects stimulus and transmits signal to the → spinal cord or brainstem
Second-order neurons?
Continues to the thalamus at the upper end of the brainstem
Third-order neurons?
Carries the signal the rest of the way to the sensory region of the → cerebral cortex
The spinothalamic tract is part of what?
Is part of the anterolateral system
Carries signals for pain, pressure, temperature, light touch, tickle, and itch
Tract is composed of axons of second-order neurons
Upper motor neurons (UMN)?
Originates in cerebral cortex or brainstem and terminates → lower motor neurons
Lower motor neurons (LMN)?
Leave the brain stem or spinal cord to communicate with → skeletal muscles
Cell bodies are in the brain stem and spinal cord
Lateral and anterior corticospinal tracts carry what?
Carry signals from cerebral cortex for precise, finely coordinated → movements
Spinal nerves?
Act as paths of communication between the spinal cord and the body
How many pairs of the cervical nerves?
8 pairs
How many pairs of the thoracic nerves?
12 pairs
How many pairs of the lumbar nerves?
5 pairs
How many pairs of the sacral nerves?
5 pairs
How many pairs of the coccygeal nerves?
1 pair
How many total nerves?
62 total pairs
Nerve pairs are connected to spinal nerve segments by two bundles of axons called?
Roots
Spinal nerves are associated with the spinal cord, but they are part of the?
PNS
Parallel bundles of axons along with connective tissue layers and neuroglia cells
Dorsal (posterior) root?
Conduct nerve impulses from sensory receptors (in skin, muscles, and internal organs) to the → CNS
Each has a swelling called the dorsal (posterior) root ganglion – contains cell bodies of sensory neurons
Ventral (anterior) root?
Contains axons of motor neurons
Send nerve impulses from the CNS through motor neurons to effectors (muscles or glands)
Reflexes?
Quick, involuntary, stereotyped reactions of glands or muscle to stimulation
Reflexes require?
Stimulation
Not spontaneous actions, but responses to sensory input
Reflexes are?
Quick
Involve few, if any, interneurons and minimum synaptic delay
Secondly, Reflexes are?
Involuntary
Occur without intent and are difficult to suppress
Thirdly, Reflexes are?
Stereotyped
Occur essentially the same way every time
Reflexes include what?
Glandular secretion and contraction of all three types of muscle
Somatic reflexes?
Reflexes involving the somatic nervous system, innervating skeletal muscle
Visceral reflexes?
Reflexes involving organs such as heart (cardiac muscle) and intestines (smooth muscle)
Reflex arc?
Nerve impulse traveling into, through, and out of the → CNS
(1) Sensory (somatic) receptor?
Dendrites of a sensory (afferent) neuron or an associated sensory structure
Responds to a stimulus – change in the internal or external environment
Produces a local potential
Reaches threshold and triggers a → action potential
(2) Sensory (afferent) neuron?
Axon receives the nerve impulse from the sensory receptor
Travels to the gray matter of the spinal cord through the dorsal (posterior) root
Relay the reflex nerve impulses to the parts of the brain responsible for → conscious awareness
(3) Integrating center?
Regions of the gray matter within the → CNS
Integration will occur in multiple regions for a complex reflex
(4) Motor (efferent) neuron?
Picks up the impulses triggered by the integrating center and sends it out of the CNS to an effector through the ventral (anterior) root
(5) Effector?
Part of the body that responds to a motor nerve impulse (muscle or gland)
The response is called a → reflex
Stretch (myotatic) reflex?
When a muscle is stretched, it “fights back” and → contracts
Helps maintain equilibrium and posture
Head starts to tip forward as you fall asleep and muscles contract to raise the head
Stretch reflex stabilizes what?
Stabilize joints by balancing tension in extensors and flexors, smoothing muscle actions
Stretch reflex is mediated primarily by?
The brain, but its spinal component can be greater if muscle is suddenly stretched by a tendon tap (knee jerk)
Knee-jerk (patellar) reflex?
Is a monosynaptic reflex arc
One synapse between the afferent and efferent neurons
Testing somatic reflexes helps diagnose many → diseases
Reciprocal inhibition?
Reflex phenomenon that prevents muscles from working against each other by inhibiting antagonist when agonist is excited
Stretching of muscle stimulates?
Sensory receptors called muscle spindles (monitor changes in muscle length)
Muscle spindles generate?
Nerve impulses that travel up somatic sensory neurons to the → CNS
Spinal cord contains the?
Integrating center, which actives a motor neuron in the gray matter
Motor neuron sends a?
Signal along its axon out to the PNS nerves to → stimulate muscle
Action potential is?
Triggered in the stretched muscle and it → contracts
At the same time, an inhibitor signal is?
Being sent out another motor (efferent) neuron
Inhibits contraction of?
The knee flexor preventing overstretching of the knee extender
Tendon reflex?
In response to excessive tension on the tendon
Inhibits muscle from contracting strongly
Moderates muscle contraction before it tears a tendon or pulls it loose from the muscle or bone
Tension is applied to a?
Tendon, tendon organ (sensory receptor) is stimulated and depolarizes
Nerve impulse travels to the CNS along a → sensory neuron
Spinal cord acts as the?
Integrating center, activates an inhibitory interneuron, which sends a signal to motor neurons
Hyperpolarization (inhibition) occurs in the motor neuron
Muscle relaxes and → eases tension
Flexor?
The quick contraction of flexor muscles resulting in the withdrawal of a limb from a painful stimulus
Triggers contraction of the flexors and relaxation of the extensors in that limb
Polysynaptic reflex arc?
Pathway in which signals travel over many synapses on their way to the muscle
If you step on something sharp dendrites of pain sensory receptors are?
Stimulated
Generates a nerve impulse to the → CNS
In the integrating center (spinal cord) activates interneurons extend to several spinal cord segments
Through ascending and descending → tracts
Interneurons activate?
Motor neurons, in several spinal cord segments, generate nerve impulses that travel to motor→ axon terminals
Motor neuron signals cause flexor muscles in the thigh to contract, making you withdraw your leg (protective)
Cross extensor reflex?
Contraction of extensor muscles in limb opposite of the one that is withdrawn
Maintains balance by extending other leg
Flexor reflex uses an?
Ipsilateral reflex arc, (stimulus and response on same side)
Crossed extension reflex uses a?
Contralateral reflex arc (input and output are on opposite sides)
Intersegmental reflex?
One in which the input and output occur at different levels (segments) of the spinal cord
Pain in foot causes contraction of abdominal muscles
If you step on a tack what happens?
Pain receptors in that foot are stimulated
Generates a nerve impulse, which goes to the→ spinal cord
Integrating center (spinal cord) activates?
Interneurons of the uninjured foot through several spinal cord segments
Pain signals move to?
The opposite side though interneurons and go several segment levels above and below the point of entry into the cord
Motor neurons are?
Excited in several spinal cord segments that connect to extensor muscles and send nerve impulses toward axon terminals
Motor neurons cause extensor muscles in the thigh (effectors) of the uninjured leg to?
Contract
Helps you to put weight on that foot to→ support the body