Gene Expression L15 (Genes & Proteins)

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11 Terms

1
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Central Dogma

DNA —> transcription —> RNA —> translation —> protein

  • unidirectional flow of genetic information


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Transcirption

information DNA used to synthesize messenger RNA

3
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Translation

ribosome uses mRNA to synthesize a polypeptide

4
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Uracil

pyrimidine base

complimentary to adenine

two hydrogen bonds

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mRNA

messenger

encodes AA sequence

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rRNA

ribosomal

structural part of ribosome

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tRNA

transfer

brings AA to ribosome during translation

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Codon

mRNA sequence

  • read in triplet (3 nucleotides

  • Codes for 1 AA

  • 64 different combos


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Wobble hypothesis

3rd bases can vary wihtout changing amino acid0 mutation tolerancec

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Frame shift

Mutation delete 1st T

  • Ex. The red dog ate the bug

    • Mutation Delete 1st T (the red one)

    • Results in a frameshift

      • her edd oga tet heb ug


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Summary

information flow DNA —> RNA —> Protein