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Hypoxia
low tissue oxygen level
places severe limits on metabolic activities of the affected area
Anoxia
inadequate oxygen reaching body tissues
kills cells very quickly
Pneumothorax
condition in which air enters the pleural cavity due to an injury to the chest wall that penetrates the parietal pleura, or ruptures the alveoli, breaking through visceral pleura
"Collapsed Lung"
Atelectasis
Collapsed lung
Eupnea
quiet breathing
inhalation involves muscular contraction, but exhalation is a passive process
Apnea
Cessation of breathing
Compliance
expandability; the ability of certain organs to tolerate changes in volume; indicates the presence of elastic fibers and smooth muscles
Hyperpnea
forced breathing
involves active inspiratory and expiratory movements
External Respiration
exchange of gases between the atmosphere and the blood
Converts deO2 to O2 blood
Pulmonary Ventilation
breathing; the exchange of gases between the atmosphere and the lungs so external respiration can then occur with the blood
Internal Respiration
exchange of gases between the blood and tissue cells
O2 to deO2 blood
Boyle's Law
the pressure of a gas in a closed container is inversely proportional to the volume of its container
Size of container doubled = gas pressure decreased by half
Diaphragmatic (deep) Breathing
contraction of diaphragm provides necessary change in thoracic volume
air drawn into lungs as diaphragm contracts, air exhaled passively when diaphragm relaxes
Costal (shallow) Breathing
thoracic volume changes because the rib cage alters its shape
inhalation takes place when contractions of the external intercostal muscles raise the ribs and enlarge the thoracic cavity
exhalation takes place passively when these muscles relax
Elastic Rebound
when muscles of inhalation relax, the elastic components recoil, returning the diaphragm, rib cage, or both to their original positions
Respiration
one inspiration and one expiration
Spirometer
device used to measure amount of air exchanged during breathing
Tidal Volume (TV)
amount of air moved in or out of respiratory passageways during inhalation or exhalation
Inspiratory Reserve Volume (IRV)
air breathed in forcibly after normal inhalation
Expiratory Reserve Volume (ERV)
air forced out after normal exhalation
Minute Volume of Respiration
total air taken in per minute
Residual Volume
amount of air remaining in lungs after expiratory reserve volume is expelled
Vital Capacity
IRV + TV + ERV
Upper Respiratory System
nose, nasal cavity, paranasal sinuses, and pharynx
Lower Respiratory System
larynx, trachea, bronchi and bronchioles, and alveoli
Respiratory tract
the passageways that carry air to and from the lung exchange surfaces
Alveoli
terminal pockets at the end of the respiratory tree, lined by a simple squamous epithelium and surrounded by a capillary network; sites of gas exchange with the blood
Respiratory mucosa
lines the conducting portion of the respiratory system
Mucosa
mucous membrane
Lamina propria
underlying layer of areolar tissue that supports the respiratory epithelium
Nasal vestibule
the space contained within the flexible tissues of the nose
Soft palate
the fleshy posterior extension of the hard palate, separating the nasopharynx from the oral cavity
Pharynx
the throat; a muscular passageway shared by the digestive and respiratory tracts
Nasopharynx
a region that is posterior to the internal nares and superior to the soft palate and ends at the oropharynx
lined by pseudostratified ciliated columnar epithelium
Oropharynx
the middle portion of the pharynx, bounded superiorly by the nasopharynx, anteriorly by the oral cavity, and inferiorly by the laryngopharynx
Stratified squamous epithelium
Laryngopharynx
the divisions of the pharynx that is inferior to the epiglottis and superior to the esophagus
Larynx
a complete cartilaginous structure that surrounds and protects the glottis and vocal cords
Thyroid cartilage
largest laryngeal cartilage
made of hyaline cartilage
forms most of the anterior and lateral walls of the larynx
Cricoid cartilage
a ring-shaped cartilage that forms the inferior margin of the larynx
protect the glottis and entrance to the trachea
Epiglottis
a blade-shaped flap of tissue, reinforced by cartilage, that is attached to the posterior and superior surface of the thyroid cartilage; folds over the entrance to the larynx during swallowing
Arytenoid cartilage
a pair of small cartilages in the larynx
Corniculate cartilage
a pair of small laryngeal cartilages
Glottis
structure within the larynx that consists of the vocal folds and the rima glottidis
Bolus
pasty mass that food is crushed and chewed into
Phonation
sound production at the larynx
Laryngitis
an infection or inflammation of the larynx
commonly affects vibrational qualities of vocal folds
hoarseness
Acute epiglottitis
swelling of epiglottis
Trachea
the windpipe; an airway extending from the larynx to the primary bronchi
Submucosa
the region between the muscularis muscosae and the muscularis externa
Bronchial tree
the trachea, bronchi, and bronchioles
Carina of trachea
a ridge that separates the openings of the right and left main bronchi at their junction with the trachea
Bonchus
branch/branches of the bronchial tree between the trachea and bronchioles
Bronchitis
difficulty breathing
Bronchodilation
the dilation of the bronchial passages; can be caused by sympathetic stimulation
Bronchoconstriction
reduction in the luminal diameter of the airway
Alveolar sacs
an air-filled chamber at the terminal end of the alveolar duct that gives rise to the alveoli in the lung
Pneumocytes type I
squamous epithelial cells that are the sites of gas diffusion
Alveolar macrophages
patrol epithelial surface
engulf any particles that have eluded other defenses
Pneumocytes type II
scattered among squamous cells
produce surfactant
Surfactant
a lipid secretion that coats the alveolar surfaces of the lungs and prevents their collapse
key role in keeping the alveoli open
Pneumonia
develops from an infection or any particle that causes inflammation within the lung
Lungs
the paired organs of breathing enclosed by the pleural cavities
Hilum
provides access for entry to pulmonary vessels, nerves, and lymphatics
Pulmonary embolism
blocking a branch of a pulmonary artery stops blood flow to a group of lobules or alveoli
Congestive heart failure
the failure to maintain adequate cardiac output due to cardiovascular problems or myocardial damage
Pleura
the serous membrane that lines the pleural cavities
Parietal pleura
covers the inner surface of the thoracic wall and extends over the diaphragm and mediastinum
Visceral pleura
covers the outer surfaces of the lungs, extending into the fissures between the lobes
Pleural fluid
moist, slippery coating
reduces friction between the parietal and visceral surfaces during breathing
Pulmonary ventilation
the movement of air into and out of the lungs
Alveolar ventilation
movement of air into and out of the alveoli
Atmospheric pressure
weight of earth's atmosphere
Inspiration
inhalation
movement of air into the respiratory system
Intrapulmonary pressure
the pressure inside the respiratory tract, at the alveoli
Intrapleural pressure
the pressure in the pleural cavity, between the parietal and visceral pleurae
Respiratory rate
the number of breaths taken each minute
Respiratory minute volume
the amount of air moved into and out of the respiratory system each minute
Tidal volume
the amount of air moved into or out of the lungs during a single respiratory cycle
Inspiratory reserve volume
the amount of air that can be taken over and above the tidal volume
Pancreatic duct
a tubular duct that carries pancreatic juice from the pancreas to the duodenum
Pancreatic juice
a mixture of buffers and digestive enzymes that is discharged into the duodenum under the stimulation of the enzymes, secretin and cholecystokinin
Pancreatitis
an inflammation of the pancreas
Pancreatic alpha-amylase
enzyme that breaks down certain starches
Carbohydrase
an enzyme that breaks down carbohydrate molecules
Pancreatic lipase
breaks down certain complex lipids, releasing products that can be easily absorbed
Nucleases
breaks down RNA or DNA
Proteolytic enzymes
break apart proteins
Proteases
an enzyme that breaks down proteins into peptides and amino acids
Elastase
a pancreatic enzyme that breaks down elastin fibers
Liver
an organ of the digestive system that has varied and vital functions, including the production of plasma proteins, the excretion of bile, the storage of energy reserves, the detoxification of poisons, and the interconversion of nutrients
Ligamentum teres
the fibrous strand in the falciform ligament of adults that is the remnant of the umbilical vein
What is the doorway to the liver?
Porta hepatis
Hepatocytes
liver cells
Lobules
basic functional units of the liver
Bile
the exocrine secretion of the liver; stored in the gallbladder and ejected into the duodenum
Hepatic ducts
the duct that carries bile away from the liver lobes and toward the union with the cystic duct
Bile duct
the duct formed by the union of the cystic duct from the gallbladder and the common hepatic duct from the liver; terminates at the duodenal ampulla, where it meets the pancreatic duct
Cystic duct
a duct that carries bile between the gallbladder and the common bile duct
Bile salts
steroid derivatives in bile; responsible for the emulsification of ingested lipids
Enterohepatic circulation
the excretion of bile salts by the liver, followed by the absorption of bile salts by intestinal cells for return to the liver by the hepatic portal vein