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integral protein
a protein that spans the entire width of the membrane. helps with transport
peripheral protein
a protein that does not span the entire width of the membrane. helps with structure
glyco-proteins
help to identify self from non-self cells.
amphipathic
hydrophobic and hydrophilic parts
What 2 ways is new membrane created?
The smooth ER makes new membrane to send to outside or when a vesicle exocytosis the membrane surrounding the vesicle is used
metabolism
totality of energy used in an organism chemical reactions
metabolic pathway
begins with a speciifc molecule and ends with a product. the pathway is catalyzed by a protein
catabolic pathway
releases energy by breaking down complex molecules to simpler compounds
anabolic pathways
consume energy to build complex molecules from simpler ones
bioenergetics
the study of how energy flows through living organisms
kinetic energy
energy of motion
thermal energy
energy generated by random movement of atoms to generate heat
heat
transfer of thermal energy between objects
potential energy
energy that matter possess because of location/structure
chemical energy
energy that is released in reaction
thermodynamics
the study of energy transformations
law 1 of thermodynamics
energy cannot be created or destroyed
law 2 of thermodynamics
energy transfer increased the entropy of the universe
spontaneous process
occur without energy. increase entropy. negative delta g
non-spontaneous process
occur with energy. decrease entropy. positive delta g
exergonic reaction
net release of free energy and is spontaneous. negative delta g
endergonic rxn
absorbs free energy, non spontaneous, positive delta g
catalyst
speeds up reaction without being consumed by reaction
enzymes
lower activation energy. catalytic protein.
substrate
reactant that an enzyme acts on
active site
where the substrate fits into the enzyme
induced fit
of a substrate brings chemical groups into positions that enhance reaction
how do enzymes lower Ea?
correct orientation of the molecules, strain substrate bonds, provide a favorable environment, covalently bond to substrate
enzyme saturation
when all the active sites are engaged
what can impact enzyme activity?
temperature and pH, chemicals that influence the enzyme
cofactor
non-protein enzyme helpers
organic cofactor
coenzyme
competitive inhibitor
bind to the active site
non-competitive inhibitor
bind to other part of the enzyme to change the shape, making the active site less effective
allosteric regulation
regulatory molecule binds to a protein at one site and affects proteins functions at another site
feedback inhibition
end product of a metabolic pathway binds to the active site to shut down the rest of the pathway
fermentation
partial degradation of sugars without oxygen
aerobic respiration
consumes organic molecules and oxygen
cellular respiration equation
C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + Energy (ATP and heat)
oxidation
loses an electron
reduction
gains an electron
How to harvest energy from glucose
glycolysis
citric acid/krebbs cycle
oxidative phosphorylation
what is the maximum amount of ATP that can be made from each molecule of glucose
32 ATP