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What is ventilation?
breathing - moving gas to site of exchange
where does gas exchange occur?
capillary beds at lungs and tissues
what are the functions of the respiratory system?
primarily gas exchange
pH balance
speech/vocalisation
protection and maintenance of lungs and rest of body
what are other metabolic functions of the respiratory system?
angiotensin 1 to angiotensin 2
prostaglandin synthesis
what structures are in the conducting portion of the respiratory system?
nose, nasal cavity and paranasal sinuses
pharynx
larynx
trachea
bronchi, bronchial tree
terminal bronchioles
what structures are in the respiratory portion of the respiratory system?
respiratory bronchioles
alveoli (ducts and sacs)
how many alveoli are there per lung?
400 million
what is the nose made up of?
cartilage, muscle, soft tissue, nasal bone
what is another word for nostrils?
nares
what cartilages are found in the nose?
septal cartilage
major alar cartilage
minor alar cartilages
what muscle acts to flare the nostrils?
nasalis
what is nasalis innervated by?
facial nerve (CN VII)
what space occurs after passing nostrils?
nasal vestibule
what epithelium is found in the nasal vestibule?
squamous
what is another word for nasal hair and what effect does it have?
vibrissae and it has a filtering effect
what organism is associated with nasal vestibulitis?
S. aureus
what is the bony structure of the nasal cavity covered by?
respiratory mucosa - respiratory epithelium
what is the floor of the nasal cavity made up of?
hard and soft palate
what bones make up the lateral wall of the nasal cavity?
ethmoid (superior and middle conchae)
inferior nasal concha
maxilla
sphenoid
palatine bone
lacrimal
nasal bone
what is the hard palate made up of?
palatine process of maxilla
horizontal process of palatine bone
what is the medial wall (septum) of the nasal cavity made up of?
perpendicular plate of ethmoid
vomer
septal cartilage
what type of epithelium is found in the nasal cavity?
respiratory (mostly)
olfactory (superiorly)
NALT (nasal associated lymphoid tissue) (posteriorly)
squamous mucosa (anteriorly)
what type of epithelium is respiratory mucosa?
cilliated psuedostratified columnar epithelium
what structures are found in respiratory mucosa?
cilliated psuedostratified columnar epithelium
goblet cells
rich vascular supply of submucosal glands
which cranial nerve is the olfactory nerve?
CN 1
what are olfactory tracts?
extensions of the forebrain
where does the olfactory nerve terminate?
the olfactory bulb
what is the pathway from the olfactory mucosa back to the brain?
olfactory mucosa → olfactory neurones → olfactory bulb → olfactory tract → medial and lateral striae → piriform cortices
what do olfactory neurones pass through?
the cribriform plate
what pathways are there into the nasal cavity?
foramen cecum
cribriform plate
sphenopalatine foramen
lateral wall foramina
incisive canal
what is the foramen cecum?
a venous connection between nasal veins and a superior sagittal sinus
what passes through the sphenopalatine foramen?
sphenopalatine artery
nasopalatine and superior nasal nerves
what passes through the lateral wall foramina?
posterior inferior nasal branches of greater palatine nerve
what passes through the incisive canal?
nasopalatine nerve
greater palatine/sphenopalatine artery
which gateway in the nasal cavity provides a pathway to the oral cavity?
incisive canal
what arteries are the anastomoses between in the nasal cavity?
branches of the internal and external carotid arteries
what do the anterior and posterior ethmoidal arteries arise from?
the ophthalmic artery which arises from the internal carotid
what do the anterior and posterior ethmoidal arteries give off?
lateral and septal branches
what do the anterior and posterior ethmoidal arteries cross?
the cribriform plate
what does the sphenopalatine artery arise from?
Maxillary artery which arises from the external carotid
what does the descending palatine artery arise from?
maxillary artery
what does the facial artery arise from?
maxillary artery
what does the sphenopalatine artery give off?
posterior lateral nasal
posterior septal
what does the descending palatine artery give off?
the greater palatine artery
what does the facial artery give off in the nasal cavity?
super labial artery
lateral and septal nasal arteries
what is the cavernous sinus joined by?
the superior ophthalmic vein
what is the issue with the venous drainage in the nasal cavity?
there are a lack of valves which can lead to infection spreading to the vein
aside from the superior ophthalmic vein, what else drains the nasal cavity?
the pterygoid plexus ad facial vein
what does the facial vein drain to?
the internal jugular
what does lymph drain to posteriorly in the nasal cavity?
retropharyngeal nodes
what does lymph drain to anteriorly in the nasal cavity?
submandibular nodes
what does the nasal cavity lymph drain to after retropharyngeal and submaibular nodes?
deep cervical lymph nodes
what is the named lymph node in the neck that can be palpated if inflamed?
jugulodigastric node
what are the main cranial nerves that innervate the nasal cavity?
olfactory (CNI)
trigeminal (opthalmic, maxillary, mandibular divisions) (CN V1,2,3)
facial (CN VII)
which part of the nasal cavity is the territory of the ophthalmic nerve?
upper half (diagonal line from nose to ear)
which part of the nasal cavity is the territory of the maxillary nerve?
lower half (diagonal line from nose to ear)
which nerve is special sensory in the nasal cavity?
olfactory nerve
which cranial nerves are somatic sensory in the nasal cavity?
V1 and V2 (ophthalmic and maxillary)
what does the opthalmic division of the trigeminal nerve branch into?
nasicillary nerve → anterior ethmoidal (lateral and septal nasal branches)
what does the maxillary division of the trigeminal nerve branch into?
nasopalatine and greater palatine nerves
what is the autonomic innervation to the nasal cavity?
facial nerve
what is the function of the facial nerve in the nasal cavity?
parasympathetic secretomotor
what is the sympathetic innervation to the nasal cavity via?
periarterial fibres - from the superior cervical ganglion
what is the different name for conchae when they are covered by mucus?
turbinates
what is the significance of the turbinates in the nasal cavity?
increase surface area and aid in warming and humidifying air
what does turbinate flow aid in and what is it called?
aids in the filtering of particles before they reach further into the airway - turbulent precipitation
what are the paranasal sinuses?
frontal
sphenoidal
maxillary
ethmoidal (anterior, middle and posterior cells)
which paranasal sinus is particularly prone to sinusitis?
maxillary sinus
what do the paranasal sinuses drain into?
the lateral aspect of the nasal cavity
what is the function of paranasal sinuses?
aid in warming and humidifying air
what is the space under a concha called?
meatus
where does the frontal sinus drain to?
the middle meatus through the ethmoidal infundibulum
what drains to the middle meatus?
frontal sinus
anterior ethmoidal air cells
maxillary sinus
where do the middle ethmoidal and posterior ethmoidal air cells drain to?
the ethmoidal bulla in the middle meatus
what does the sphenoidal sinus drain to?
the spheno ethmoidal recess - located posterior and superior to the superior concha
what does the maxillary sinus drain to?
the middle meatus via the semilunar hiatus
what drains to the inferior meatus?
the nasal lacrimal duct (from the lacrimal apparatus of the eye)(runny nose when cry)
what is the growth of nasal cavities from childhood called?
pneumatization
where do paranasal sinuses drain?
to the nasal cavity
what exists below each conchae?
a space called a meatus
what does the frontal sinus drain to?
middle meatus via frontonasal duct and ethmoidal infundibulum
where do anterior ethmoidal cells drain to?
middle meatus via ethmoidal infundibulum
where do middle ethmoidal cells drain to?
middle meatus (ethmoidal cells)
where do posterior ethmoidal cells drain to?
superior meatus
where does the maxillary sinus drain?
middle meatus via semilunar hiatus
where does the sphenoidal sinus drain?
sphene-ethmoidal recess
where does the nasolacrimal duct drain?
the inferior meatus
what are clinical implications that could affect paranasal sinuses?
sinusitis, fractures/trauma, maxillary dentition, pituitary gland tumour
what nerve supplies the frontal sinus?
Supra orbital (CN V1)
what nerves supply the ethmoidal sinus?
Ant. And post. Ethmoidal (Nasociliary from CN V1)
Orbital branches CN V2 from pterygopalatine ganglion
what nerves supply the sphenoidal sinus?
Post. Ethmoidal (Nasociliary from CN V1)
Orbital branches CN V2 from pterygopalatine ganglion
what nerves supply the maxillary sinus?
Infra orbital and superior alveolar branches maxillary nerve (CN V2)
what artery supplies the frontal sinus?
anterior ethmoidal (ophthalmic)
what arteries supply the ethmoidal sinus?
anterior and posterior ethmoidal (ophthalmic)
what arteries supply the sphenoidal sinus?
pharyngeal arteries (maxillary)
what arteries supply the maxillary sinus?
infraorbital and superior alveolar branches of maxillary artery
what is the first part of the pharynx?
nasopharynx
what does the nasopharynx communicate with the nasal cavity via?
choanae
what does the nasopharynx become below the soft palate?
orthopharynx
what is the sensory innervation to the nasopharynx?
pharyngeal branch of CN V2