Steps of a G protein coupled receptor signal transduction ( BMED 5207 exam 4)

Step 1 of a G protein coupled receptor signal transduction

a sigmal molecule binds the receptor, activiting it

step 2 of a G protein coupled receptor signal transduction

the receptor changes conformation and binds an inactive G protein

step 3 of a G protein coupled receptor signal transduction

the G protein is activated b the dissociation of GDP and binding GTP

step 4 of a G protein coupled receptor signal transduction

the g protein alpha subunit dissociates from beta/gamma subunit

step 5 of a G protein coupled receptor signal transduction

the dissociated G protein alpha and beta/gamma subunits activate effectors, leading to a cellular response

stpe 6 of a G protein coupled receptor signal transduction

the GTPase activity of the G protein alpha subunit hydrolyzes GTP to GDP

step 7 of a G protein coupled receptor signal transduction

the GDP-bound G protein alpha subunit reassociates with beta/gamma subunit, terminating G protein signal