PNB 2265 innate/ stereotypic

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8 Terms

1
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what are the two types of stereotypic response

fever and inflammation

2
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fever

caused by pyrogens > increase metabolic rate

inhibits

bacterial toxin release

replication

also allows the travel time of WBC to be faster

3
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what do pyrogens allow

they are sent out and could be endogenous cell

aimed at hypothalamus, this is where temperature is controlled

4
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so after foreign threats…..

external, then internal barriers

comes stereotypic response

5
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goal of stereotypic response

amplify immune response

6
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inflammation at site of injury leads to

  1. vasodilation increases rate immune cells come to the site of the injury

complement and antibodies

opsonization

both of these work to help phagocytosis and flagging

  1. chemotaxis

  2. permeability of capillaries increases


7
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chemotaxis

attraction of WBC to chemicals such as histamine

8
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what happens when permeability of capillaries increases

proteins and larger cells now have a easier time getting out into tissues where they can deal with damage or pathogen that is present

factor of inflammation at site of injury