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What is Alzheimer's disease, what neurotransmitter is involved, and what does it affect?
Progressive brain disorder
Linked to low acetylcholine
Mainly affects memory, learning, and thinking
Causes memory loss and confusion
What are the symptoms, causes, and treatments of Alzheimer's disease
Symptoms:
Memory loss
Confusion
Difficulty thinking and speaking
Trouble with everyday tasks
Cause:
Brain cells become damaged and die
Reduced acetylcholine levels
Treatment:
No cure
Medication may help manage symptoms
Memory support and cognitive activities
What is Parkinson's disease, what neurotransmitter is involved, and what does it affect?
Progressive neurological disorder
Linked to low dopamine
Mainly affects movement and coordination
Causes difficulty controlling movement
What are the symptoms, causes, and treatments of Parkinson's disease?
Symptoms:
Tremors (shaking)
Muscle stiffness
Slow movement
Balance problems
Cause:
Loss of dopamine-producing neurons
Treatment:
Dopamine medications
Exercise and physical therapy
Sometimes brain stimulation surgery
Describe the structure of the CNS
Brain and spinal cord.
Describe the structure of the PNS
All nerves outside the CNS.
What are the two branches of the PNS
Somatic NS (voluntary) and Autonomic NS (involuntary).
What does the Somatic NS control
Voluntary skeletal muscle movement.
What does the Autonomic NS control
Involuntary functions of organs and glands.
What are the two branches of the Autonomic NS
Sympathetic (fight/flight) and Parasympathetic (rest/digest).
What is the role of the spinal cord
Transmits messages between brain and body; enables reflexes.
What is a monosynaptic reflex
Reflex with one synapse: sensory neuron → motor neuron.
What is a polysynaptic reflex
Reflex with interneurons: sensory → interneuron → motor.
Why are spinal reflexes important
Fast, automatic responses that increase survival.
What is localised brain function
Specific functions linked to specific cortical areas.
What is distributed brain function
Functions spread across multiple brain regions.
What does the frontal lobe do
Movement, planning, decision‑making, personality, language production.
What does the parietal lobe do
Somatosensory processing and spatial awareness.
What does the temporal lobe do
Auditory processing, language comprehension, memory.
What does the occipital lobe do
Vision and visual processing.
Where are explicit memories stored
Hippocampus (formation), neocortex (long‑term storage), amygdala (emotional tagging).
Where are implicit memories formed
Basal ganglia (motor sequences, habits) and cerebellum (coordination, procedural learning).
What is the role of Broca’s area
Speech production. In the frontal lobe
What is the role of Wernicke’s area
Language comprehension. in the temporal lobe
What is Geschwind’s territory
Connects Broca’s and Wernicke’s areas; integrates multimodal language information. in parietal Lobe
What does the primary motor cortex do
Initiates voluntary movement.
What does the cerebellum do in movement
Coordinates balance, timing, smooth movement; stores procedural motor memories.
What do the basal ganglia do in movement
Select, refine and sequence voluntary movements; inhibit unwanted movements.
How do these areas interact
Basal ganglia plan → cerebellum coordinates → motor cortex executes.
What does the limbic system do
Processes emotion, motivation and memory.
What does the amygdala do
Generates fear and emotional responses; emotional memory.
What does the hippocampus do
Forms explicit memories and links emotion to memory.
What does the prefrontal cortex do
Regulates emotions, decision‑making, impulse control.
What is an action potential
An electrical impulse that travels down a neuron.
What is synaptic transmission
Neurotransmitters cross the synapse and bind to receptors on the next neuron.
What is an excitatory neurotransmitter
Increases likelihood of neuron firing (e.g., glutamate).
What is an inhibitory neurotransmitter
Decreases likelihood of neuron firing (e.g., GABA).
What does acetylcholine do
Muscle contraction, REM sleep, learning and memory; low levels linked to Alzheimer’s.
What does epinephrine do
Fight/flight response; increases heart rate and arousal.
What does norepinephrine do
Arousal, alertness, mood and concentration; low levels linked to depression and ADHD.
What does dopamine do
Motor control (low = Parkinson’s), reward, motivation, pleasure.
What does serotonin do
Mood regulation, sleep, appetite; low levels linked to depression.
What causes Parkinson’s disease
Loss of dopamine‑producing neurons in the basal ganglia.
What are symptoms of Parkinson’s disease
Tremors, rigidity, slow movement, balance issues.
What are treatments for Parkinson’s disease
L‑DOPA, dopamine agonists, deep brain stimulation.
What causes Alzheimer’s disease
Amyloid plaques, neurofibrillary tangles, reduced acetylcholine.
What are symptoms of Alzheimer’s disease
Memory loss, confusion, personality changes.
What are treatments for Alzheimer’s disease
ACh‑boosting medications, cognitive therapy (no cure).
How does vision begin (reception)
Cornea bends light → pupil regulates light → lens focuses → retina receives image.
What is visual transduction
Rods and cones convert light into electrical signals.
How is visual information transmitted
Optic nerve → optic chiasm → thalamus (LGN).
Where is visual information processed
Primary visual cortex (occipital lobe).
How is visual information interpreted
Temporal lobe identifies objects; parietal lobe judges location.
How does hearing begin (reception)
Pinna funnels sound → ossicles amplify → cochlea vibrates.
What is auditory transduction
Hair cells in the organ of Corti convert vibrations into electrical signals.
How is sound transmitted
Auditory nerve → thalamus (MGB).
Where is sound processed
Primary auditory cortex (temporal lobe).
Where is sound interpreted
Wernicke’s area for language; other areas for pitch, loudness, timbre.
What is perceptual set
A predisposition to perceive stimuli based on past experience, context, motivation, emotion.
How does past experience affect perception
Previous experiences shape interpretation of stimuli.
How does context affect perception
Environment influences how stimuli are interpreted.
How does motivation affect perception
We see/hear what we want or expect.
How does emotion affect perception
Emotional state biases interpretation.
What are visual constancies
Stable perception despite changes in retinal image.
What is size constancy
Perceiving size as constant despite distance changes.
What is shape constancy
Perceiving shape as constant despite angle changes.
What are Gestalt principles
Ways the brain organises visual information into wholes.
What is figure‑ground
Distinguishing an object from its background.
What is closure
Filling in gaps to perceive a whole image.
What is similarity
Grouping similar elements.
What is proximity
Grouping elements that are close together.
What are binocular depth cues
Depth cues requiring both eyes (retinal disparity, convergence).
What are monocular depth cues
Depth cues using one eye (linear perspective, interposition, texture gradient, relative size, height in visual field).
What is loudness
Perception of amplitude (dB).
What is pitch
Perception of frequency (Hz).
What is timbre
Quality of sound due to waveform complexity.
What did de Bruine et al. (2018) find
Cultural background influences eyewitness visual memory accuracy.
What did Patel & Demorest (2013) find
Musical perception varies across cultures depending on exposure.
What is the multi‑store model
Memory has sensory, short‑term and long‑term stores.
What is sensory memory
Brief storage of sensory information; iconic (0.3s), echoic (3–4s).
What is STM
12–30 seconds, capacity 5–9 items.
What is LTM
Unlimited capacity and duration.
What is the working memory model
STM is active with four components: central executive, phonological loop, visuospatial sketchpad, episodic buffer.
What does the central executive do
Controls attention and coordinates memory systems.
What does the phonological loop do
Stores auditory information.
What does the visuospatial sketchpad do
Stores visual/spatial information.
What does the episodic buffer do
Integrates information and links to LTM.
What is the levels of processing model
Deeper encoding → better memory; structural, phonemic, semantic processing.
What is implicit memory
Unconscious memory (procedural, priming, classical conditioning).
What is explicit memory
Conscious memory (episodic and semantic).
What is the role of the hippocampus in memory
Forms and consolidates explicit memories.
What is the role of the neocortex in memory
Long‑term storage of explicit memories.
What is the role of the amygdala in memory
Emotional tagging of memories.
What is the role of the cerebellum in memory
Forms implicit procedural memories.
What is recall
Retrieving information without cues.
What is recognition
Identifying correct information among options.
What is relearning
Learning information again faster due to savings.
What is encoding failure
Information not stored due to lack of attention or shallow processing.
What is retrieval failure
Stored information cannot be accessed due to missing cues.
What is interference
When other information blocks retrieval.