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What is the optimal duration for breastfeeding (exclusive and total time)?
Exclusively for 6 months, then until 2 years or beyond
How are exclusive breastfeeding rates for infants 0-5 months in relation to the world average?
48% of infants are exclusively breastfed under 6 months globally
Grape like clusters that contain the secretory cells for secreting milk (where milk is made):
Alveoli in mammary glands
Which hormone is released from the pituitary gland and stimulates milk to eject into ducts?
Oxytocin that act on myoepithelial cells
What benefits does breastfeeding provide to the mother?
Prevents breast and ovarian cancer and diabetes
Calorie burning
Lower depression risk
Uterine healing
Stronger bond
What benefits does breastfeeding provide to the baby?
Could save lives
Longer breastfeeding durations associated with higher scores on intelligence tests
Reduces risk of non communicable diseases and decreases prevalence of overweight or obese in life
Helps avoid diarrhea episodes and respiratory infection
Which hormone is released from the pituitary gland and stimulates milk production from secretory cells?
Prolactin
Colostrum: amount consumed, macronutrient distribution, electrolytes
secreted during the first few days postpartum
Very high in proteins, low carbs and fat
Yellow color
Highest concentration of immune cell components and antibodies
Low amount consumed
Mature milk: amount consumed, macronutrient distribution, electrolytes
Primary energy source
Low in protein, high in carbs and fat
Lower in antibodies and immune cells because diluted by volume
Hindmilk
received at the end of a breastfeeding session
contains more fat and calories
needed for growth and development
thicker and creamier
Foremilk
received at the beginning of a feeding session, it helps baby’s thirst and contains lactose and proteins, but few fat and calories
Benefits/differences between breast milk and formula
Breast milk adapt’s to infants needs and provides live antibodies. It is easier to digest and provides immune boosting factors
Instant formula is manufactured, but provides consistent nutritional alternative that offers caregiver flexibility. Infant formulas are fortified with vitamin D
DHA requirements and benefits during lactation
200-300 mg/day
increases membrane fluidity (brains, eyes, CNS)
enlarges lipoprotein particles
better transmission of signals
essential for retinal development
associated with higher IQ
found in seafood
2 servings fatty fish/week
protein requirements during lactation
additional 25 g of protein
calorie requirements during lactation
energy needs varies by activity level
600ml/day=700 cal
+330 kcal/day for the 1st 6 months and +400 kcal/day afterward
prevention strategies for engorgement
nurse frequently—newborns may nurse every 1-2 hrs
prevention strategies for letdown failure
relaxation techniques
massaging
moist heat
prevent strategies for plugged ducts
complete emptying of breasts and changing position of infant while feeding
lecithin to emulsify fat in milk
prevention strategies for infection
feed on demand
don’t skip feedings
drain the breast
alternate sides
recommendations for alcohol
wait 2-3 hours after drink
recommendations for nicotine and tobacco
can transfer into breast milk. so avoid
wait at least 95 mins after smoking
nicotine can lower prolactin and oxytocin levels
caffeine recommendations
limit daily intake, only 1% in plasma
can make baby more active
artificial sweeteners recommendations
small amounts of sweeteners can alter taste of breast milk and could mild digestive sensitivity
amount of time breastmilk can be stored in the fridge and freezer
fridge 4 days
freezer 6 months
hormones affecting milk production and lactogenesis
prolactin
insulin
progesterone
oxytocin
hormones altered in breast milk
leptin
insulin
ghrelin
vitamin D recs
400 IU
vitamin K recs for infants
single dose injection .5-1 mg
frequency of feeding for infants
10-12 times per day
letdown failure
when milk does not eject from the breast
very uncommon
oxytocin nasal spray may be prescribed
hyperactive letdown
streams of milk from from breast
mother should express milk until the flow slows then allow infant to nurse
engorgement
breast are overfilled
results with supply and demand process not yet established
infection
mastitis is inflammation of the breast
1-33% of women
may be infective or non infective
common at 2-3 weeks postpartum
low milk supply
diet, stress, not emptying breasts, not feeding enough, use of estrogen
galatogogue drug used to increase prolactin levels
gag reflex
prevents infant from taking things into lungs
oral search reflex
infant opens mouth wide when close to breast and thrusts tongue forward
rooting reflex
infant turns to side when stimulated on that side
hormones impacting lactation
estrogen
progesterone
human growth hormone
human placenta lactogen
prolacftin
oxytocin
estrogen on lactation
ductal growth
mammary glands differentiation with menstruation
progesterone on lactation
alveolar development
after onset menses and during pregnancy
human growth hormone on lactation
development of terminal end buds
mammary gland development
human placenta lactogen on lactation
alveolar devleopment
pregnancy
prolactin on lactation
alveolar development and milk secretion
pregnancy and breastfeeding]
inhibits ovulation
oxytocin on lactation
letdown
from onset of milk secretion to weaning
prevents hemorrhaging
lowers BP
stages of lactogenesis
1: milk formation begins
2: increased blood flow to breast; milk comes in
3: milk composition is stable
casein
facilitates calcium absorption
gives milk white appearance
whey
immunoglobulins, enzymes
some minerals, hormones, and vitamin binding proteins
more in early milk
both whey and casein in late milk
non protein nitrogen
~20-25% nitrogen in human milk
used to make nonessential amino acids
benefits of protein in milk
growth factors
binding prtoeins
bifidus factor
enzymes
lactose
dominant carb
enhances calcium absorption
oligosaccharides
medium length carb
second dominant
prevents binding of pathogenic microorganisms to gut, preventing infection and diarrhea
vitamin A
content in colostrum is double that of mature milk
yellow color from beta carotene
vitamin E
level linked to milks’ fat content
not adequate
vitamin K prevents
blood clotting
water soluble vitamins reflect
mothers diet
most likely deficient water soluble vitamin
b6
vitamin b12 and folate
bound to whey
trace minerals in milk
zinc: bound to protein and highly available. rare defect in mammary gland uptake of zinc may cause zinc deficiency that appears as a diaper rash
flouride: influenced by mothers diet
high lactose content of foremilk may
cause diarrhea or greenish stools
vitamin d in milk
prevents and treats rickets
provides ling long benefits
benefits of WIC
free breast pump
counseling
food assistance
food packages
who is eligible for WIC?
breastfeeding women
pregnant women
children
low income
exercise and breastfeeding
moderate exercise
aerobic activity enhances fatty acid mobilization
restriction in energy intake enhances prolactin
tooth decay
caries can occur in children who are breastfed
risk factor frequency after 1 year
all children should be seen 6 months after 1st tooth or at 1 yr
cholesterol
higher in human milk
appears to be related to lower blood cholesterol levels later in life
effect of maternal diet on fat composition
fatty acid profile reflects mothers diet
low dat diet with adequate carbs and protein, milk is increased in medium chain fatty acids
how do HMOs influence cognitive development?
prebiotics diminish gut imbalance and reduces inflammation from immature intestine to developing brain
increased formation of short chain fatty acids which are substrates for brain signaling