E7 : Protein synthesis (mRNA translation)

Describe the three steps of eukaryotic protein synthesis (mRNA translation)

Describe how translation is regulated

Outline the key elements and relevance of post translational processing

What are the differences between eukaryotic and prokaryotic protein synthesis? What is the significance for drug targeting such as antimicrobial therapy

What are the key components for translation

How is the transcribed code for a gene translated into a defined protein? Why are there 61 possible codons for 20 amino acids

Outline key elements of initiation, elongation and termination in translation

What is the significance of targeting ribosomes to the cytoplasm / endoplasmic reticulum

What are polysomes

Name some examples of post translational modification and relevance to protein function

How and why are proteins degraded

How can the process of translation be targeted by drugs for conditions like microbial infections