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vibramycin
doxycycline
antibacterial
therapeutic class of doxycycline/vibramycin
tetracycline
pharmacologic class of doxycycline/vibramycin
minocin
minocycline
antibacterial
therapeutic class of minocycline/minocin
tetracycline
pharmacologic class of minocycline/minocin
binds to the 30s subunit to prevent protein synthesis
MOA of tetracyclines doxycycline/minocycline)
photosensitivity
chelates with calcium
major characteristic of tetracyclines (doxy/minocycline)
bactrim
septra
sulfamethoxazole/trimethoprim (SMX/TMP)
antibacterial
therapeutic class of bactrim
sulfonamide + dihydrofolate reductase inhibitor
pharmacologic class of bactrim
blocks steps in folic acid pathway
MOA of bactrim
cleocin
clindamycin
antibacterial
therapeutic class of clindamycin/cleocin
lincosamide
pharmacologic class of clindamycin/cleocin
binds to 50s subunit of ribosome to prevent RNA synthesis
MOA of clindamycin/cleocin
macrobid
macrodantin
nitrofurantoin
antibacterial
therapeutic class of macrobid/nitrofurantoin
nitrofuran
pharmacologic class of nitrofurantoin/macrobid
disrupts protein synthesis by forming toxic metabolites
MOA of nitrofurantoin/macrobid
only concentrates in bladder
major characteristic of nitrofurantoin/macrobid
flagyl
metronidazole
antibacterial
antiprotozoal
therapeutic class of metronidazole/flagylni
nitroimidazole
pharmacologic class of metronidazole/flagyl
disrups protein synthesis by forming toxic metabolites (free radicals)
MOA of metronidazole/flagyl
GI upset
metallic taste
major characteristic of metronidazole/flagyl