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Negative feedback loop
Primary way our body maintains homeostasis. When something is moved away from its set point (too cold) your body will counteract it (shivering to warm you up)
Allostasis
You body anticipating the need for change and making it before it needs to. Kind of stress related. High allostasis causes heart issues and such.
Glucose vs Glycogen
Glucose is immediate, glycogen is stored.
Glucagon and Insulin
Insulin tells your body to convert excess glucose into glycogen. Glucogon tells the body to convert glycogen into glucose.
Lateral hypothalamus
Primary hub for motivating you to eat.
Ventromedial Hypothalamus
Tells you to stop eating.
Arcuate Nucleus
Similar to VMH, lesion it and you will be obese. No blood brain barrier. balances energy metabolism and reproduction
Ghrelin
Produced by stomach, hunger signal
Hunger supressing hormones
Leptin, PPY, CCK, Insulin
OVLT
No blood brain barrier, osmoreceptors, sensative to sodium levels, detects fluid levels.
Endotherms vs Ectotherms
Endo=warm Ecto=cold (blooded)
Preoptic Area of the Hypothalamus (POA)
Body temperature control
Pituitary Gland
Master gland that releases a bunch of hormone. growth, metabolism, stress response, and reproduction
Sexual Dimorphism
Male and female look different outside of genitals.
Primary vs Secondary Sex Characteristics
Primary (present since birth) Secondary appear after pubert
Brain differences between men and women
Very similar, mens are a little bigger. Men are more connected front to back brain while women are more connected left to right brain.
Mullerian vs Wolffian Systems/Ducts
Mullerian in woman Wolffian in Men. Either disintegrate depending on which sex is picked.
Helen Fisher’s Stages of Love and their relationship with hormones/neurotransmitters
1: Lust, test and est. 2: Attraction, Dopamine and Norepinephrine, less seratonin. 3: Attatchment, oxytocin, vasopressin.
Oxytocin
Love chemical, also helps with childbirth and moving sperm.
Vasopressin and Oxytocin’s impact on Prairie and Montane Voles
Parie voles have more love hormone receptors and form pair bonds. Montane voles are bops but when their brain is changed to have more love hormone receptors they become bonders.
What causes masculinization of the brain?
Testosterone and it converting into estradiol in the fetal period.
Affect
Energy/ general mood. Positive vs negative.
james-lange
Stimulus —> Physiological Response (e.g., racing heart, trembling) —> Conscious Emotion (e.g., fear)
cannon-bard
the brain triggers both the body and the mind at the exact same time.
schacter-singer
Stimulus → Physiological Response → Cognitive Appraisal→Conscious Emotion. (racing heart can mean love or anxiety depending on context)
Ventromedial Prefrontal Cortex (vmPFC)
values the payoff of choices (is this worth it or not)
Amygdala
Fear part of brain.
Lateral Nucleus of Amygdala
learning part of amygdala. classical conditioning,
Basal Nucleus of Amygdala
Proceses context of fear, where and when
Central Nucleus of Amygdala
Coordinates fight or flight
dPAG vs vPAG (Periaqueductal Grays)
dPAG is involved in action (flight and fight) vPAG is involved in freezing, relaxing and pain supression.
Distress vs Eustress
Distress=Bad, demands exceed ability to cope.
Eustress=Good, energizing, you can do task
SAM System
Fast stress response, Hypothalamus → Sympathetic NS, Adrenaline and Noradrenaline. Fight or Flight
HPA Axis
Slow stress response, Hypothalamus → Pituitary Gland → Adrenal Cortex, Corticotropin-Releasing Hormone (CRH), ACTH, and Cortisol (glucocorticoids).
Glucocorticoids
steroids that reduce inflamation, supress immune system, regulate glucose, protein, and fat metabolism. (cortisol)
Adverse Childhood Experiences (ACEs)
abuse, neglect, and household challenges that can traumatize children under 17.
Nonassociative learning
learning to adjust responses to a repeated stimulus.
Habituation = reduce response
Sensitization = increase response
Perforant Pathway
information entry of hippocampus. encoding, consolidating, and retrieving declarative and spatial memories.
Hebbs rule
Neurons that fire together, wire together. two connected neurons are activated at the same time, the-synapse between them grows stronger, making it easier for one neuron to trigger the other in the future
how long-term potentiation (LTP) occur
persistent strengthening of a chemical synapse following high-frequency or repeated stimulation. Glutamate is released, Ampa, nmda.
AMPA receptors
fast excitatory regulators, sodium rushes in.
NMDA receptros
slower, longer lasting signals, nueroplasticity, sodium and calcium.