Discussion Paper 5

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4 Terms

1
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What happens to tuft cell numbers in presence of T. muris and other extracellular parasites

tuft cell numbers increase

2
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What is tuft cell expansion after T. muris dependent on

taste-chemosensory pathways

3
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What is the chemosensory pathway tuft cells use

TPRM5 signalling in tuft cells produces IL-25 which promotes expansion of ILC2s which produces IL-13 which promotes expansion of Tuft cells

4
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What is the stimulatory signal for tuft cell population expansion

ILC2-derived IL-13