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Surgical excision during thyroid surgery
Hypoparathyroidism
Fatal tenany (spasms in larynx) due to decline of blood calcium
Hypoparathyroidism
Excess PTH secretion
Hyperparathyroidism
Parathyroid tumor
Hyperparathyroidism
Bones become soft, fragile, and deformed, promotes renal calculi formation
Hyperparathyroidism
inner core, 10% to 20% of gland
Adrenal medulla
Both an endocrine gland and a ganglion of the sympathetic nervous system
Adrenal medulla
Innervated by sympathetic preganglionic fibers
Adrenal medulla
Consists of modified sympathetic postganglionic neurons
called chromaffin cell
Adrenal medulla
When stimulated, release catecholamines
Adrenal medulla
Catecholamines
Epinephrine and norepinephrine
Mobilize high-energy fuels, lactate, fatty acids, and glucose
Adrenal medulla
Glycogenolysis and gluconeogenesis by liver
Adrenal medulla
Inhibits insulin secretion (glucose-sparing effect)
Epinephrine
Mineralocorticoids is found in the
Adrenal Cortex
The main mineralocorticoids is called
Aldosterone
Cause the kidneys to retain sodium and water and excrete potassium, increasing blood volume and blood pressure.
Aldosterone
Glucocorticoids is found in the
Adrenal Cortex
The main glucocorticoids is called
Cortisol
Raise blood glucose, promote fat and protein breakdown, help the body respond to stress, and suppress inflammation.
Cortisol
Sex steroids is found in the
Adrenal Cortex
Set libido throughout life; large role in prenatal male development
Androgens
Important after menopause
Estradiol
Excess cortisol secretion
Cushing syndrome
Hyperglycemia, hypertension, weakness, edema
Cushing syndrome
Rapid muscle and bone loss due to protein catabolism
Cushing syndrome
Abnormal fat deposition; moon face and buffalo hum
Cushing syndrome
Adrenal androgen hypersecretion (accompanies Cushing
Adrenogenital syndrome
Enlargement of external sexual organs in children and early
onset of puberty
Adrenogenital syndrome
Masculinizing effects on women
Adrenogenital syndrome
Deficient cortisol and/or aldosterone
Addison’s Disease
Hypoglycemia, Hypotension, Weakness, Weight loss, and Hyperpigmentation
Addison’s Disease