Biomed Top 300 Week 1

Potassium Chloride (oral) Brand

Klor-Con®, K-Dur®, Micro-K®

Potassium Chloride Class

Electrolyte

Potassium Chloride Indications

Hypokalemia

Potassium Chloride MOA

Maintenance of the excitatory properties of neuromuscular tissues, and the resting membrane potential of cells

Hydrochlorothiazide Brand

Microzide®

Hydrochlorothiazide Class

Thiazide Diuretic, Antihypertensive

Hydrochlorothiazide Indications

Edema, Hypertension

Hydrochlorothiazide MOA

Increase sodium and chloride excretion by interfering with their reabsorption in the cortical diluting segment of the nephron

Furosemide Brand

Lasix®

Furosemide Class

Loop Diuretic

Furosemide Indications

Edema of volume overload related to heart failure, renal failure

Furosemide MOA

Decreases sodium reabsorption by competing for the chloride site on the Na+-K+-2Cl- cotransporter

Torsemide Brand

Demadex®

Torsemide Class

Loop Diuretic

Torsemide Indications

Edema related to heart failure, renal failure, hepatic cirrhosis, hyptertension

Torsemide MOA

Loop diuretic - decreases sodium reabsorption by competing for the chloride site on the Na+-K+-2Cl- cotransporter

Enoxaparin Brand

Lovenox®

Enoxaparin Class

Anticoagulant, Low-Molecular-Weight Heparin

Enoxaparin Indications

DVT prophylaxis and treatment, Acute ST-segment elevation AMI, Unstable angina

Enoxaparin MOA

Anti-factor Xa and IIa properties

Warfarin Brand

Coumadin®, Jantoven®

Warfarin Class

Anticoagulant, Vitamin K Antagonist

Warfarin Indications

Atrial fibrillation; myocardial infarction; prosthetic cardiac valve component embolism; pulmonary embolism; thrombosis, post-myocardial infarction; venous thromboembolism

Warfarin MOA

Prevents the conversion of vitamin K back to its active form from vitamin K epoxide. This impairs formation of the vitamin K-dependent clotting factors II, VII, IX, and X (prothrombin) and proteins C and S (physiologic anticoagulants)

Folic Acid Class

Essential B Vitamin

Folic Acid Indications

Megaloblastic and macrocytic anemia

Folic Acid MOA

Conversion of deoxyuridylate to thymidylate, which is a rate-limiting step in DNA synthesis