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Science
Zygote
A fertilized egg that undergoes repeated cell division after a sperm fertilizes an egg.
Differentiation
A process that creates special structures and functions, allowing specialized cells to become tissues, organs, and organ systems.
Stem Cells
Undifferentiated cells that can become differentiated into one or more types of specialized cells.
Embryonic Stem Cells
Cells that have never differentiated and retain the ability to become any cell type.
Adult Stem Cells
Partially differentiated cells found in adult bone marrow that can only become certain types of cells.
Organism
One individual member of a species.
Organ System
A set of organs working together for a common function, such as the digestive system.
Organ
A set of tissues working together for a common function, such as the stomach.
Tissue
A group of cells working together for a common function, such as muscle tissue.
Cell
The most basic unit of life that possesses all the characteristics of life.
Cell Cycle
A repeated pattern of growth, DNA duplication, and cell division occurring in eukaryotic cells for growth and repair.
Interphase
The growth phase of the cell cycle comprising G1, S, and G2 phases, resulting in 2 full sets of chromosomes by its end.
G1 Phase
The Gap 1 phase of interphase in which the cell grows and synthesizes proteins.
S Phase
The Synthesis phase of interphase during which DNA replication occurs, doubling the number of chromosomes.
G2 Phase
The Gap 2 phase of interphase involving additional cell growth and protein synthesis.
Chromosome
One long continuous thread of DNA containing thousands of genes and regulatory information.
Gene
A specific section of DNA containing instructions for making a protein.
Homologous Chromosomes
Matching pairs of chromosomes in normal body cells, with half inherited from the biological mother and half from the biological father.
Chromatid
One half of a duplicated chromosome.
Sister Chromatids
Two identical chromatids attached to each other.
Centromere
The pinched region of condensed chromosomes that holds sister chromatids together.
Telomere
The protective ends of a DNA molecule.
Mitosis
The division phase of the cell cycle where 1 cell divides into 2 identical daughter cells.
Prophase
The phase of mitosis where chromosomes condense into visible sister chromatids (X's), the nuclear membrane disappears, and spindle fibers form out of centrioles.
Metaphase
The phase of mitosis where spindle fibers attach to centromeres and chromosomes align along the middle of the cell.
Anaphase
The phase of mitosis where sister chromatids separate to opposite poles of the cell, becoming individual chromosomes.
Telophase
The phase of mitosis where chromosomes decondense into threadlike chromatin, nuclear membranes re-form at each pole, spindle fibers break down, and cytokinesis begins.
Cytokinesis
The process of cytoplasm division into 2 individual cells, beginning at the end of mitosis.
Cleavage Furrow
A structure formed in animal cells during cytokinesis that pinches the cell into 2 equal parts.
Cell Plate
A structure formed midway between divided nuclei in plant cells during cytokinesis that gradually develops into a cell membrane.
External Signals
Regulatory signals originating outside the cell, such as hormones and nutrients.
Internal Signals
Regulatory signals originating from inside the cell's nucleus, such as DNA.
Checkpoint
A critical point in the cell cycle where 'stop' and 'go' signals regulate progression through phases such as G1, S, G2, and M.
Apoptosis
Programmed cell death triggered by internal or external signals that activate self-destructive enzymes.
Cancer
Uncontrolled cell division occurring when normal cell cycle regulation breaks down.
Tumor
A clump of cells dividing uncontrollably.
Benign
Describing abnormal cells that remain clustered together, typically being harmless and easily removable.
Malignant
Describing cancer cells that break away from a primary tumor and spread to other parts of the body.
Metastasize
The spreading of disease or cancer cells from one organ to other parts of the body.
Carcinogens
Cancer-causing agents and chemicals that mutate DNA, such as tobacco smoke and asbestos.