Antibiotics and Their Mechanisms

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8 Terms

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Polymyxin B
Disrupts the cell membrane, damaging its integrity.
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Chloramphenicol
Blocks peptide bond formation at the 50S ribosomal subunit, inhibiting protein synthesis.
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Tetracyclines
Block tRNA from attaching to the 30S ribosomal subunit, preventing protein synthesis.
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Ciprofloxacin
Inhibits DNA gyrase and topoisomerase IV, interfering with DNA replication.
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Rifampin
Inhibits bacterial RNA polymerase, preventing RNA synthesis.
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Penicillins
Inhibit cell wall biosynthesis, preventing bacteria from building proper cell walls.
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Vancomycin
Binds to peptidoglycan building blocks and prevents proper cell wall formation.
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Bacitracin
Stops movement of peptidoglycan ingredients from the cytoplasm to the cell wall.