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Comprehensive vocabulary flashcards focusing on integumentary structure, physiology, dermatologic disorders, diagnostic tests, medical treatments, and surgical procedures from Chapter 3 of Medical Language Sixth Edition.
Dermatology
The medical specialty that studies the anatomy and physiology of the integumentary system.
Epidermis
The thin, outermost layer of the skin composed of epithelial tissue.
Dermis
The thick layer of skin directly beneath the epidermis, composed of connective tissue containing collagen, elastin, blood vessels, and nerves.

Skin Structure
The layered anatomical unit consisting of the outer epidermis, the inner dermis, and the underlying subcutaneous tissue with accessory structures.
Keratin
A hard, fibrous protein found in dead epidermal surface cells, hair shafts, and nails that creates a strong protective barrier.
Melanocyte
A pigment-producing cell in the basal layer of the epidermis that makes melanin to absorb UV light.
Collagen
Firm, white protein fibers present in the dermis that give structural strength to the skin.
Elastin
Elastic, yellow protein fibers in the dermis that allow the skin to stretch and recoil.

Dermatome
A specific area of skin that sends sensory input through a single spinal nerve to the spinal cord; also refers to a surgical instrument.
Sebaceous glands
Exocrine oil glands located in the dermis that secrete sebum through ducts into hair follicles.
Sudoriferous glands
Exocrine sweat glands located in the dermis that secrete sweat through ducts opening onto pores at the skin surface.
Piloerection
The contraction of a tiny muscle at the base of a hair follicle in response to cold, causing the hair shaft to stand upright.

Nail Structure
Anatomical structure composed of living and dead cells comprising the nail plate, nail root, lunula, cuticle, and nail bed.
Lunula
The white, crescent-shaped area at the base of a fingernail or toenail.
Subcutaneous tissue
Loose connective tissue containing lipocytes situated beneath the dermis (abbreviated sub Q or subcu).
Thermoregulation
The physiological process of adjusting body temperature through fat storage, sweating, piloerection, and dermal blood vessel dilation.
Homeostasis
The process of maintaining internal balance and stability across body systems.
Dermatitis
Any inflammation or infection of the skin.
Edema
Excessive accumulation of fluid moving from the blood into the dermis or subcutaneous tissue, leading to swelling.

Pitting edema
Severe tissue edema in which fingertip pressure displaces fluid and creates a temporary deep indentation.
Hemorrhage
An injury to blood vessels that causes blood to escape into the skin tissue.
Lesion
Any observable abnormal structural change or damage in the skin resulting from injury or disease.
Cyst
An elevated circular mound lesion filled with semisolid or partly fluid material.
Fissure
A small, cracklike crevice lesion in the skin that may contain fluid exudate.
Macule
A flat circular skin lesion with brown or black pigmentation and no fluid content (e.g., freckle, age spot).
Papule
An elevated, solid skin lesion of normal skin color or erythema (e.g., acne pimple).
Pustule
An elevated skin lesion with a white top filled with pus (e.g., acne whitehead).
Vesicle
An elevated lesion with a transparent pointed top filled with clear fluid (e.g., herpes, chickenpox).
Wheal
An elevated lesion with a broad, flat pale top and erythematous base containing clear fluid (e.g., insect bite, urticaria).
Pruritus
Intense skin itching caused by histamine release during an allergic reaction.
Xeroderma
Excessive dryness of the skin.
Albinism
A genetic condition in which melanocytes produce little or no melanin, resulting in lack of pigment in skin, hair, and irises.
Cyanosis
A bluish-purple discoloration of skin and nails caused by insufficient oxygenation.
Erythema
Redness or red discoloration of the skin over local or extensive body areas.
Jaundice
Yellowish discoloration of skin, sclera, and mucous membranes associated with high bilirubin levels.
Necrosis
A gray-to-black skin discoloration occurring in areas where tissue death has occurred.
Vitiligo
A progressive autoimmune disease where melanocytes are destroyed, leading to patches of depigmentation.
Abrasion
A scraping or sliding mechanical injury that strips away the epidermal skin layer.
Superficial burn
A first-degree burn involving only the epidermis, causing erythema, pain, and swelling without blistering.
Full-thickness burn
A third-degree burn destroying epidermis, dermis, and underlying tissues, causing local anesthesia due to nerve destruction.

Rule of Nines
A standardized clinical calculation tool used to estimate the percentage of total body surface area affected by burns.
Cicatrix
Fibrous connective tissue composed of collagen that forms during the healing of a skin wound; a scar.
Keloid
An abnormally large, firm scar that extends beyond the original wound boundary due to overproduction of collagen.
Laceration
A linear penetrating skin wound with either clean cut or torn, ragged margins.
Pressure injury
Ulcerative skin breakdown caused by persistent pressure over bony prominences interrupting blood flow.
Abscess
A localized collection of pus beneath the skin triggered by a bacterial infection; includes furuncles and carbuncles.
Cellulitis
A spreading bacterial infection involving the skin, subcutaneous tissue, and deeper muscle layers.
Tinea
A fungal infection of the skin feeding on epidermal cells, producing scaly, pruritic lesions.
Verruca
An irregular, rough skin growth caused by human papillomavirus; a wart.
Pediculosis
An infestation with parasitic lice and their eggs (nits) in hair-bearing skin regions.
Scabies
A skin infestation caused by parasitic mites that tunnel under the skin, generating intense itching and tiny vesicles.
Urticaria
An allergic skin condition marked by transient, raised, pruritic edematous areas (hives or wheals).
Actinic keratosis
A rough, sandpaper-like precancerous skin lesion that develops on areas with chronic sun exposure.
Hemangioma
A benign, congenital mass of superficial, dilated blood vessels.
Lipoma
A benign, soft, movable subcutaneous tumor composed of adipose tissue.
Nevus
A benign congenital mole or birthmark varying in shape, elevation, and color.
Syndactyly
A congenital anomaly in which skin and soft tissue fuse adjacent fingers or toes together.
Basal Cell Carcinoma
The most common form of skin cancer, originating in the basal layer as a slow-growing pearly bump.
Malignant Melanoma
An aggressive, fast-growing skin cancer arising from melanocytes that rapidly metastasizes.
ABCDE of Melanoma
Clinical criteria for evaluating skin lesions: Asymmetry, Border irregularity, Color variation, Diameter greater than 6 mm, and Evolving size or shape.
Psoriasis
An autoimmune skin condition marked by rapid epidermal proliferation, causing red plaques covered with silvery scales.
Scleroderma
An autoimmune disorder causing abnormal collagen accumulation that hardens skin and visceral organs.
Systemic lupus erythematosus
An autoimmune disorder affecting collagen in connective tissue throughout the body, often producing a facial butterfly rash.
Acne vulgaris
A chronic inflammatory skin condition of adolescence where hardened sebum plugs hair follicles, forming comedos.
Rosacea
A chronic facial skin disorder causing facial erythema, flushing, and superficial telangiectasias in middle-aged adults.
Seborrhea
Excessive sebum production occurring outside of adolescence, causing greasy skin alternating with dry scaling or dandruff.
Anhidrosis
A congenital absence of sweat glands resulting in the inability to sweat or tolerate heat.
Diaphoresis
The physiological process of sweating; excessive profuse sweating may signal systemic illness.
Alopecia
Pathological or age-related loss of hair from the scalp.
Hirsutism
Excessive dark, thick hair growth in a male-pattern distribution on a female.
Onychomycosis
A fungal infection of fingernails or toenails causing thickening, discoloration, and deformation of the nail plate.
Culture and sensitivity
A diagnostic lab test (C&S) where wound exudate is cultured to identify causative bacteria and test antibiotic responsiveness.
Wood lamp
A ultraviolet light procedure used in a darkened room to highlight fungal infections and depigmented skin areas.
Cryosurgery
The application of extreme cold, such as liquid nitrogen, to destroy skin lesions.
Debridement
The removal of necrotic, contaminated, or damaged tissue from a wound to foster healing.
Incision and drainage
A minor surgical procedure (I&D) using a scalpel cut to evacuate accumulated fluid or pus from a cyst or abscess.

Hypodermic Injection
An injection route where a syringe needle is angled at 45^\bar{o} to deliver medication directly into the subcutaneous tissue.

Punch Biopsy
A diagnostic procedure using a cylindrical blade to extract a full-thickness tissue core sample containing epidermis, dermis, and subcutaneous tissue.
Mohs surgery
Microscopically controlled surgery to excise complex skin cancers layer by layer while preserving healthy surrounding tissue.
Rhytidectomy
Surgical removal of facial wrinkles and loose skin; commonly referred to as a facelift.