treatment of asthma/copd - drugs

SABA def

short acting beta agonist

LABA def

long acting beta agonist

SAMA def

short acting muscarinic antagonist

LAMA def

long acting muscarinic antagonist

bronchodilators examples

• beta agonists

• muscarinic antagonists

• xanthines

anti-inflammatories

• corticosteroids (ics)

• leukotriene modifiers (ltra)

• anti IgE antibodies

• biologics

examples of saba

• salbutamol

• terbutaline

examples of laba

• salmeterol

• formoterol

examples of ics

• beclomethasone

• budesonide

• fluticasone

LTRA example

montelukast

why are ANTAGONISTS used at MUSCARINIC receptors

blocks receptors and prevents some bronchoconstriction

why are AGONISTS used at ADRENERGIC receptors

activates receptors and results in bronchodilation (B2)

parasympathetic

bronchoconstriction

sympathetic =

bronchodilation

MART therapy def

• single-inhaler asthma treatment

• combines an ics (inflammation) with formoterol (LABA)

what is MART therapy used for

daily prevention and sudden-symptom relief

AIR therapy def

• single combination inhaler

• ics and formoterol to treat inflammation

AIR therapy use

relieve symptoms only when they occur

when are LTRAs used

with MART for preventation - NOT USED IN COPD

LTRA pathway

• blocks effects of cysteinyl leukotrienes in airways
  • LTC4, LTD4, LTE3

• relaxes airways