Pharmaceutical Aids and Necessities (Inorganic Medicinals - Part 2)

Boric Acid H3BO3

• Weak Acid

• Sassolite (Native)

• Solid in Room Temperature

• Colorless, odorless, pearly scales

• Six scaled triclinic crystals

• White odorless powder (unctuous)

• For External Use Only

• Component of Boroglycerin Glycerite NF - suppository base

• Toxicity: Boiled Lobster Appearance: reddish-orange skin rash (due to PO/dermal absorption)

Phosphoric acid H3PO4

• Weak Acid

• component of phosphate buffer system

• solvent in the preparation of Anileridine Injection NF (analgesic/opioid)

• Toxicity: Hypocalcemia - Decrease in bone density and even cause osteoporosis and fractures

Hydrochloric acid HCI

• Strong Acid

• Muriatic acid

• Aqueous solution of hydrogen chloride

• Pepsinogen-(HCI)—> Pepsin [Proteolytic enzyme] (breakdown of proteins)

• Chief Cells - secretes Pepsinogen

• Parietal Cells - secretes HCI & Intrinsic factor

• Tx. Gastric Achlorhydria (absence of HCI in stomach/GI Tract)

• Acidifying agent used to convert water insoluble organic bases to a water-soluble form

Nitric Acid HNO3

• Strong Acid

• Aqua Fortis

• Xanthoproteic Reagent (to detect proteins)

Sulfuric Acid H2SO4

• Strong Acid

• Oil of vitriol

• With 10% of dissolved SO3 - “oleum”

• Dehydrating agent in Pyroxylin USP preparation.