Self Care Exam 2 - Drug Class, MOA & Names

Hydrocortisone Brand name?

(Cortizone-10 and Cortaid)

Hydrocortisone (Cortizone-10 and Cortaid) Class?

Corticosteroids

Hydrocortisone (Cortizone-10 and Cortaid) MOA for topical use on the skin:

Causes mild vasoconstriction to reduce inflammation and has antipruritic activity

Colloidal oatmeal brand name?

(Aveeno Soothing Bath Treatment)

Calamine lotion brand name?

(Caladryl)

Colloidal oatmeal, Calamine lotion, Zinc Oxide, Titanium dioxide Class?

Anti-pruritics

Anti-pruritics MOA

soothe skin to provide relief from itching, discomfort, and irritation (all products)

Calamine lotion MOA

acts as an astringent to absorb fluids from oozing vesicles

Zinc Oxide + Titanium dioxide MOA

skin protectants

Zinc Oxide MOA

Works as mild astringent with weak antiseptic properties

Zinc oxide + Calamine Lotion + Creams MOA

Absorb fluids from weeping lesions. NOTE: Ointments will not do this.

Aluminum acetate 5% solution brand name?

(Burows and Domeboro Solution)

Aluminum acetate 5% solution (Burows and Domeboro Solution) Class?

Astringent

Aluminum acetate 5% solution (Burows and Domeboro Solution) Wet dressing/Compress MOA

cool and dry the skin through evaporation.

Aluminum acetate 5% solution (Burows and Domeboro Solution) MOA

Decreases edema, exudation, and inflammation by reducing cell membrane permeability and by hardening the intercellular cement of the capillary epithelium. Causes vasoconstriction and reduces blood flow in inflamed tissue Cleanses the skin of exudates, crust, and debris.

Benzocaine 20% brand name?

(Lanacaine)

Lidocaine 0.5% brand name?

(Solarcaine)

Pramoxine 1%, Benzyl alcohol 10% brand name?

(Itch-X)

Benzocaine, Lidocaine, Pramoxine, Benzyl alcohol Class?

Local anesthetic

Benzocaine, Lidocaine, Pramoxine, Benzyl alcohol Class MOA

Local, reversible blockade of conduction of nerve impulses (through inhibition of sodium channels and depolarization)

Menthol Class?

Analgesic/anti-pruritic

Camphor 0.1-3% brand name?

(Blue Star, Sarna)

Camphor 0.1-3% (Blue Star, Sarna) Class

Analgesic/Anti-pruritic + Counterirritant

Camphor 0.1-3% (Blue Star, Sarna) Analgesic/Anti-pruritic MOA

Depresses cutaneous receptors at concentrations <3%. (= depresses cutaneous receptors) – from musculoskeletal matrix

Camphor 0.1-3% (Blue Star, Sarna) Analgesic/Anti-pruritic Counterirritant MOA

Counterirritant – 3-11% stimulates nerve endings to produce a mild sensation of pain/discomfort (cool sensation)– from musculoskeletal matrix

Topical diphenhydramine 1% brand name?

(Benadryl Spray)

Topical diphenhydramine 0.5-2% brand name?

(Benadryl Gel, Allegra Anti-itch Cream)

Topical diphenhydramine 1% + diphenhydramine 0.5-2% Class

Local antihistamine with local anesthetic

Topical diphenhydramine 1% + diphenhydramine 0.5-2% MOA

Depress cutaneous histamine receptors

Oral Diphenhydramine brand name?

(Benadryl)

Oral Diphenhydramine Class

Antihistamine

Oral Diphenhydramine MOA

Compete with histamine at central and peripheral H1 receptors to prevent mediator

Tecnu MOA

chemical inactivator

Dial Ultra dishwashing soap or Dawn MOA

surfactant to remove from skin

Goop grease remover MOA

removes oil from skin

Zanfel MOA

surfactant to remove from skin

Bentoquatam brand name?

(Ivy Block)

Bentoquatam (Ivy Block) MOA

Organoclay substance, which is capable of absorbing or binding to urushiol, the active principle in poison oak, ivy, and sumac. Serves as a physical barrier, blocking urushiol skin contact/absorption.

DEET 4-100% MOA

Releases vapors that discourage the approach of insects (does not kill insects).

Picaridin--- 5%, 10%, 20% MOA

Releases vapors that discourage the approach of insects (does not kill insects)

Water-based lotions brand name?

(Lubriderm)

(Lubriderm) Class?

Water-based lotions

(Lubriderm) MOA

Soothe skin while maintaining skin moisture and texture, absorbs into skin and dissipates excessive moisture

Talc and cornstarch Class

Protectant

Talc and cornstarch MOA

Both absorb excess fluid and acts as a lubricant when applied to dry skin and will reduce friction

White petrolatum (30-100%), cocoa butter (50-100%), petrolatum (30-100%), allantoin (0.5-2%)

(Aquaphor Healing Ointment, CeraVe Healing Ointment, Vaseline, Palmer’s)

White petrolatum (30-100%), cocoa butter (50-100%), petrolatum (30-100%), allantoin (0.5-2%) Class

Skin protectant

White petrolatum (30-100%), cocoa butter (50-100%), petrolatum (30-100%), allantoin (0.5-2%) MOA

Softens and moisturizes stratum corneum; protects from mechanical irritation caused by friction and rubbing

Hydrogen peroxide (3%) MOA

Tissue debriding agent releases oxygen briefly on contact with tissue enzymes to debride and cleanse tissues through effervescent mechanical debridement; lyses cells

Isopropyl alcohol (70%) MOA

kills bacteria on contact

Bacitracin, polymyxin B, neomycin brand name?

(Neosporin)

Bacitracin, polymyxin B brand name?

(Polysporin)

Topical Honey MOA

Delivers a moist, wound-healing environment, absorbs exudate, has antibacterial, antifungal, and anti-inflammatory properties

Silver gel MOA

inhibits the growth of both gram-positive and gram-negative bacteria

Liquid bandage brand name

(8-hydroxyquinoline 1%)

Liquid bandage (8-hydroxyquinoline 1%) MOA

forms a clear, flexible coating over the injury, protecting the tissue

Aloe Vera GEL MOA

Contains vitamins, minerals, and enzymes which promote wound healing and may have anti-inflammatory and antimicrobial properties

Bacitracin MOA

inhibits cell wall synthesis in gram positive bacteria

bacitracin + polymyxin B (Polysporin) MOA

alters cell wall permeability which causes leakage from intracellular contents in gram negative bacteria

bacitracin + polymyxin B + neomycin (Neosporin) MOA

irreversibly binds to the 30S ribosomal subunit inhibiting protein synthesis in gram negative bacteria; covers anaerobes (aminoglycoside antibiotic)

Bacitracin, polymyxin B, neomycin Class

Antibiotic

Liquid bandage (8-hydroxyquinoline 1%) / Silver gel Class

Topical wound healing products

Aminobenzoic acid (PABA), anthranilates (meradimate), benzophenones (UVA and UVB- dioxybenzone, oxybenzone), cinnamates (cinoxate, octinoxate, octocrylene=UVA/B), dibenzoylmethane derivatives (avobenzone), salicylic acid derivatives class

Chemical sunscreen ingredients

Aminobenzoic acid brand name

(PABA)

anthranilates brand name

(meradimate)

benzophenones brand name

(UVA and UVB- dioxybenzone, oxybenzone)

cinnamates brand name

(cinoxate, octinoxate, octocrylene=UVA/B)

dibenzoylmethane derivatives

(avobenzone)

Chemical sunscreen ingredients MOA

Absorb and block transmission of the UVR into the epidermis

Zinc Oxide, titanium dioxide class

Physical Sunscreens

Zinc Oxide, titanium dioxide MOA

Physically reflects and scatters all UV rays