med term bone disorders

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Last updated 12:02 AM on 9/27/26
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17 Terms

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osteoporosis

a condition where bone tissue degrades and mineral density drops, leaving bones brittle and prone to fractures from minimal impact

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osteopenia

early-stage loss of bone density that is less severe than osteoporosis but elevates fracture risk

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Paget’s Disease of Bone

chronic condition where normal bone remodeling is disrupted, causing new bone to form too quickly and structurally weak, leading to deformities and bone pain

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Rickets & Osteomalacia

softening and weakening of bones caused by severe Vitamin D, calcium, or phosphate deficiency

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Osteoarthritis (OA)

degenerative joint disease caused by the gradual breakdown of protective articular cartilage, leading to bone-on-bone, pain, and stiffness

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Rheumatoid arthritis (RA)

an autoimmune disorder where immune system attacks synovium (joint lining), causing systemic inflammation, pain, and joint deformity

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Gout

Metabolic arthritis caused by high blood levels of uric acid, which form sharp urate crystals in joint spaces, causing sudden intense pain (frequently targeting the big toe)

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Ankylosing spondylitis

Inflammatory arthritis that causes vertebrae in the spine to fuse overtime, reducing spinal flexibility and altering posture

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Bursitis

Inflammation of the fluid-filled sacs (bursae) that cushion bones, tendons, and muscles near joints

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Osteogenesis imperfecta (“brittle bone disease”)

A genetic connective tissue disorder caused by defective collagen production, resulting in fragile bones that break easily

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Achondroplasia

A genetic bone growth disorder causing dwarfism, characterized by shorter limbs and normal trunk length

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Fibrodysplasia Ossificans Progressiva (FOP)

A rare genetic disorder where muscle and connective tissue are gradually replaced by bone (heterotropic ossification), locking joints in place

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Scoliosis/kyphosis/lordosis

Structural spinal curvature deformities affecting alignment (sideways curve in scoliosis, exaggerated upper back in kyphosis, inward lower back arch in lordosis)

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Osteomyelitis

A severe bacterial or fungal infection inside the bone or bone marrow, leading to localized tissue destruction

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Avascular necrosis (osteonecrosis)

Bone death caused by temporary or permanent loss of blood supply to the tissue, often leading to joint collapse (commonly at the hip)

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Osteosarcoma

A primary malignant bone cancer that originates in the bone-forming cells, most often occurring near the ends of long bones

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Osgood-Schlatter disease

Inflammation of the patellar ligament at the tibial tuberosity (apophysitis) usually affecting adolescents during growth spurts