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1300s
The Italian Renaissance begins in northern Italian city-states.
1304-1374
Lifetime of Petrarch ("Father of Humanism").
1315-1317
The Great Famine
1337-1453
Hundred Years' War
1347-1353
The Black Death (Bubonic Plague) in Western Europe
1378-1417
The Papal Schism (Western Schism)
1380s
John Wycliffe translates the Bible into English
1405
Leonardo Bruni writes On Learning and Literature.
1415
Jan Hus is burned at the stake for heresy in Bohemia.
1419
Prince Henry establishes a school for navigators in Portugal.
1420-1436
Filippo Brunelleschi constructs the Dome of Florence Cathedral.
1450
Johannes Gutenberg invents the mechanical printing press.
1453
Fall of Constantinople to the Ottoman Empire.
1469
Marriage of Ferdinand of Aragon and Isabella of Castile.
1488
Bartholomeu Dias rounds the southern tip of Africa (Cape of Good Hope).
1492
Muslim Granada falls, completing the Spanish Reconquista.
Christopher Columbus makes his first voyage across the Atlantic.
1494
Treaty of Tordesillas is signed between Spain and Portugal.
1498
Vasco da Gama reaches India.
1509
Desiderius Erasmus publishes Praise of Folly.
1513
Niccolò Machiavelli writes The Prince.
1515
Pope Leo X issues a papal bull to raise funds for rebuilding St. Peter’s Basilica.
1516
Thomas More publishes Utopia.
1517
Martin Luther posts his 95 Theses.
1519
Hernán Cortés lands in Mexico (Aztec conquest completed 1521).
Ferdinand Magellan sets sail (First circumnavigation of the earth completed in 1522).
Charles V is elected Holy Roman Emperor.
1521
Diet of Worms
1524-1525
The German Peasants’ War
1530-1535
Francisco Pizarro conquers the Inca Empire.
1534
The Act of Supremacy.
The MĂĽnster Rebellion.
1536
John Calvin publishes Institutes of the Christian Religion.
1540
Society of Jesus (Jesuits) established under Ignatius Loyola.
1545-1563
Pope Paul III invoked The Council of Trent.
1555
The Peace of Augsburg.
1556
Charles V abdicates the throne.
1558
Coronation of Queen Elizabeth I of England.
1559
The Catholic Church issues the first Index of Prohibited Books.
1562-1598
The French Wars of Religion.
1568-1648
The Eighty Years' War.
1571
Battle of Lepanto.
1572
St. Bartholomew’s Day Massacre.
1576
Jean Bodin publishes Six Books of the Commonwealth.
1588
Defeat of the “Invincible” Spanish Armada.
1589
Henry of Navarre ascends the French throne as King Henry IV.
1598
Henry IV issues the Edict of Nantes.
1600
British East India Company founded.
1602
Dutch East India Company (VOC) founded.
1603
James I ascends the English throne.
1607
Jamestown, Virginia founded.
1608
Samuel de Champlain founds Quebec (New France).
1610
Assassination of King Henry IV of France.
1618
The Thirty Years' War (1618–1648).
1648
The Peace of Westphalia:
Recognizes Calvinism alongside Lutheranism and Catholicism.
Grants official independence to the Dutch Republic and Swiss Confederation.
Weakens the Holy Roman Empire and establishes the modern sovereign state system.