Describe the underlying pathophysiology associated with Vitamin B12 deficiency and hematological/neurological clinical presentation

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Last updated 5:21 AM on 9/30/26
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8 Terms

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vitamin b 12 is needed for

RBC/DNA synthesis and for the nervous system

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B12 deficiency causes both

hematological and neurological symptoms 

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low b12 causes what type of anemia

microcytic anemia

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what is Pernicious anemia

specific type of b12 deficiency anemia, body not able to absorb vitamin b12 properly 

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pernicious anemia is because of

lack of intrinsic factor 

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Intrinsic factor

protein made by stomach that is needed to absorb B12 

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with low intrinsic factor that means…

we cant absorb b 12 ultimately leading to macrocytic anemia

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Neurological presentation 

You get numbness, tingling, unsteady gait