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Homeostasis
Active maintenance of internal condition within ranges compatible with cell and organism function
Internal Environment
Fluid surroundings of the body’s cells, especially extracellular fluid, whose conditions affect cell function
Regulate Variable
Physiological quantity, such as core temperature, that a control system monitors and influences
Set Point
Reference value around which a regulated variable is maintained; can change with physiological circumstances
Normal Range
Range of values compatible with normal function under specified conditions
Thermoregulation
Processes that control body temperature by changing heat production or heat exchange
Ectotherm
Animal whose body heat comes mainly from surroundings
Endotherm
Animal whose body heat comes mainly from its own metabolism
Metabolism
Chemical reactions that sustain life, including reactions that transfer energy and release heat
Protein
Molecule made of one or more polypeptide chains that can perform structural, catalytic, transport, or signaling functions
Aging
Changes over time that can reduce physiological function and resilience
Stimulus
Detectable change in internal or external conditions that can initiate a response
Sensor/Receptor
Component that detects a condition or change and provides information to a regulatory system
Control Center
Component that integrates information and coordinates the appropriate response
Effector
Cell, tissue, or organ that carries out a response directed by a control system
Response
Change in activity produced by an effector following a signal
Negative Feedback
Response that opposes a change in the regulated variable, helps stabilize that variable
Positive Feedback
Response that reinforces an initiating change, increasing its effect until the loop is interrupted or reaches an endpoint
Feedback Loop
Regulatory arrangement in which the result of a response influences subsequent system activity
Hypothalamus
Region of the brain that that coordinates several homeostatic processes, including body temperature regulation