CC - Apoproteins, Lipoproteins, Important Lipid Disorders

Apo-A

HDL

Apo-B48

Chylomicrons

Apo-B100

LDL and VLDL

Apo C-I and C-II

Chylomicrons and VLDL

Apo C-III

VLDL and HDL

Apo-E

IDL and chylomicrons

chylomicrons

main transporter of EXOGENOUS TAG

VLDL

main transporter of ENDOGENOUS TAG

LDL

transports cholesterol to peripheral tissue

HDL

transports cholesterol form tissue to liver (reverse cholesterol transport pathway)

IDL

Carry endogenous TAG and cholesterol

Lipoprotein (a)

sinking prebeta lipoprotein

lipoprotein X

found in obstructive jaundice and LCAT deficiency

B-VLDL

found in type 3 hyperlipoproteinemia

Tangier disease

markedly reduced or almost deficient HDL

Bassen-Kornzweig syndrome

Defective apo-B synthesis (no VLDL, LDL, CM)

Anderson’s disease

Defective Apo-B48

Sitosterolemia

plant sterols are absorbed and accumulate in the body